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| | 2-Pyridinecarboximidamide,N-hydroxy-5-methoxy-(9CI) Basic information |
| | 2-Pyridinecarboximidamide,N-hydroxy-5-methoxy-(9CI) Chemical Properties |
| Boiling point | 317.5±52.0 °C(Predicted) | | density | 1.32±0.1 g/cm3(Predicted) | | storage temp. | Inert atmosphere,Store in freezer, under -20°C | | pka | 14.21±0.50(Predicted) |
| | 2-Pyridinecarboximidamide,N-hydroxy-5-methoxy-(9CI) Usage And Synthesis |
| Synthesis | The general procedure for the synthesis of N-hydroxy-5-methoxy-2-pyridine carboxamides from 5-methoxypicolinonitrile is as follows: using the standard method for the synthesis of kainamidoxime, an ethanol (4 mL) solution of 2-cyano-5-methoxypyridine (270 mg, 2.01 mmol), hydroxylamine hydrochloride (0.457 mL, 5 M, 2.28 mmol), and sodium hydroxide (0.230 mL, 10 N, 2.30 mmol) were mixed and heated to reflux for 24 hours. After standard post-treatment, 79 mg of 5-methoxypyridin-2-ylamidoxime was obtained in 24% yield. | | References | [1] Patent: US2003/55085, 2003, A1 |
| | 2-Pyridinecarboximidamide,N-hydroxy-5-methoxy-(9CI) Preparation Products And Raw materials |
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