| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:4-PQBH
CAS:2243355-51-1
Purity:99.08% Package:1removed
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Benzoic acid, 4-(4-quinolinylamino)-, 2-(4-pyridinylmethylene)hydrazide manufacturers
- 4-PQBH
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- $69.00
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2026-06-06
- CAS:2243355-51-1
- Purity: 99.08%
- Supply Ability: 10g
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| | Benzoic acid, 4-(4-quinolinylamino)-, 2-(4-pyridinylmethylene)hydrazide Basic information |
| | Benzoic acid, 4-(4-quinolinylamino)-, 2-(4-pyridinylmethylene)hydrazide Chemical Properties |
| density | 1.25±0.1 g/cm3(Predicted) | | pka | 12.06±0.46(Predicted) | | form | Solid | | color | Off-white to light yellow |
| | Benzoic acid, 4-(4-quinolinylamino)-, 2-(4-pyridinylmethylene)hydrazide Usage And Synthesis |
| Uses | 4-PQBH is a potent Nur77 binder (KD=1.17 μM). 4-PQBH extensively induces caspase-independent cytoplasmic vacuolization and paraptosis through Nur77-mediated ER stress and autophagy. 4-PQBH can be used for cancer research[1]. | | IC 50 | Nur77/NR4A1 | | References | [1] Baicun Li, et al. Discovery of a Nur77-mediated cytoplasmic vacuolation and paraptosis inducer (4-PQBH) for the treatment of hepatocellular carcinoma. Bioorg Chem. 2022 Apr;121:105651. DOI:10.1016/j.bioorg.2022.105651 |
| | Benzoic acid, 4-(4-quinolinylamino)-, 2-(4-pyridinylmethylene)hydrazide Preparation Products And Raw materials |
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