N-[2-[[4-[[4-(2,6-Dimethylphenoxy)-2-pyrimidinyl]amino]-1-piperidinyl]carbonyl]-1H-indol-5-yl]methanesulfonamide

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N-[2-[[4-[[4-(2,6-Dimethylphenoxy)-2-pyrimidinyl]amino]-1-piperidinyl]carbonyl]-1H-indol-5-yl]methanesulfonamide Suppliers list
Company Name: Shanghai Yifei Biotechnology Co. , Ltd.  
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N-[2-[[4-[[4-(2,6-Dimethylphenoxy)-2-pyrimidinyl]amino]-1-piperidinyl]carbonyl]-1H-indol-5-yl]methanesulfonamide Basic information
Product Name:N-[2-[[4-[[4-(2,6-Dimethylphenoxy)-2-pyrimidinyl]amino]-1-piperidinyl]carbonyl]-1H-indol-5-yl]methanesulfonamide
Synonyms:N-[2-[[4-[[4-(2,6-Dimethylphenoxy)-2-pyrimidinyl]amino]-1-piperidinyl]carbonyl]-1H-indol-5-yl]methanesulfonamide;HIV-1 inhibitor-54
CAS:2771211-71-1
MF:C27H30N6O4S
MW:534.63
EINECS:
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Mol File:2771211-71-1.mol
N-[2-[[4-[[4-(2,6-Dimethylphenoxy)-2-pyrimidinyl]amino]-1-piperidinyl]carbonyl]-1H-indol-5-yl]methanesulfonamide Structure
N-[2-[[4-[[4-(2,6-Dimethylphenoxy)-2-pyrimidinyl]amino]-1-piperidinyl]carbonyl]-1H-indol-5-yl]methanesulfonamide Chemical Properties
Boiling point 782.1±70.0 °C(Predicted)
density 1.399±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted)
pka9.04±0.30(Predicted)
Safety Information
MSDS Information
N-[2-[[4-[[4-(2,6-Dimethylphenoxy)-2-pyrimidinyl]amino]-1-piperidinyl]carbonyl]-1H-indol-5-yl]methanesulfonamide Usage And Synthesis
UsesHIV-1 inhibitor-54 is a potent HIV-1 inhibitor. HIV-1 inhibitor-54 has anti-HIV activity in MT-4 cells against WT HIV-1 (strain IIIB) with an EC50 value of 0.032 μM. HIV-1 inhibitor-54 can be used for the research of virus infection[1].
IC 50HIV-1
References[1] Ming W, et al. Hybrids of delavirdine and piperdin-4-yl-aminopyrimidines (DPAPYs) as potent HIV-1 NNRTIs: Design, synthesis and biological activities. Eur J Med Chem. 2023 Feb 15;248:115114. DOI:10.1016/j.ejmech.2023.115114
N-[2-[[4-[[4-(2,6-Dimethylphenoxy)-2-pyrimidinyl]amino]-1-piperidinyl]carbonyl]-1H-indol-5-yl]methanesulfonamide Preparation Products And Raw materials
Tag:N-[2-[[4-[[4-(2,6-Dimethylphenoxy)-2-pyrimidinyl]amino]-1-piperidinyl]carbonyl]-1H-indol-5-yl]methanesulfonamide(2771211-71-1) Related Product Information
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