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| | 8-bromoguanosine triphosphate Basic information |
| Product Name: | 8-bromoguanosine triphosphate | | Synonyms: | 8-bromoguanosine triphosphate;8-Bromo-GTP (aqueous solution);8-Bromoguanosine-5'-triphosphate sodium salt - 10 mM aqueous solution;8-Bromo-GTP;8-Bromoguanosine-5'-triphosphate;Guanosine 5'-(tetrahydrogen triphosphate), 8-bromo-;8-Bromo-GTP (aqueous solution), GTP analog;Guanosine, 5′-O-[bis(4-methoxyphenyl)phenylmethyl]-8-bromo-2′-deoxy-N-[(dimethylamino)methylene]-, 3′-[2-cyanoethyl bis(1-methylethyl)phosphoramidite] | | CAS: | 23197-98-0 | | MF: | C10H15BrN5O14P3 | | MW: | 602.08 | | EINECS: | | | Product Categories: | | | Mol File: | 23197-98-0.mol |  |
| | 8-bromoguanosine triphosphate Chemical Properties |
| density | 2.97±0.1 g/cm3(Predicted) | | pka | 0.97±0.50(Predicted) |
| | 8-bromoguanosine triphosphate Usage And Synthesis |
| Uses | 8-Br-GTP, a GTP analog, is a competitive FtsZ polymerization and GTPase activity (Ki of 31.8 μM) inhibitor. 8-Br-GTP can be used for nucleic acid modification[1]. | | References | [1] Tilman Lppchen, et al. GTP analogue inhibits polymerization and GTPase activity of the bacterial protein FtsZ without affecting its eukaryotic homologue tubulin. Biochemistry. 2005 May 31;44(21):7879-84. DOI:10.1021/bi047297o
[2] Jozef Hritz, et al. Optimization of replica exchange molecular dynamics by fast mimicking. J Chem Phys. 2007 Nov 28;127(20):204104. DOI:10.1063/1.2790427 |
| | 8-bromoguanosine triphosphate Preparation Products And Raw materials |
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