| Company Name: |
Tianjin Kailiqi Biotechnology Co., Ltd.
|
| Tel: |
15076683720 |
| Email: |
klq@cw-bio.com |
| Products Intro: |
Product Name:PP5-IN-1 CAS:1022417-69-1 Purity:大于98% Package:1g,5g,10g,25g根据客户需要分装 Remarks:Not For Human Use, Lab Use Only.
|
|
| | PP5-IN-1 Basic information |
| Product Name: | PP5-IN-1 | | Synonyms: | PP5-IN-1;N-(4-Benzylphenyl)-3,5-dimethylisoxazole-4-sulfonamide;4-Isoxazolesulfonamide, 3,5-dimethyl-N-[4-(phenylmethyl)phenyl]- | | CAS: | 1022417-69-1 | | MF: | C18H18N2O3S | | MW: | 342.41 | | EINECS: | | | Product Categories: | | | Mol File: | 1022417-69-1.mol |  |
| | PP5-IN-1 Chemical Properties |
| Boiling point | 524.359±60.00 °C(Press: 760.00 Torr)(predicted) | | density | 1.285±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | | solubility | DMSO: Soluble: = 10 mg/ml Ethanol: Soluble: = 10 mg/ml | | form | Solid | | pka | 6.962±0.50(predicted) | | color | Yellow to orange |
| | PP5-IN-1 Usage And Synthesis |
| Uses | PP5-IN-1 (Compound P053) is a competitive inhibitor of Serine/threonine protein phosphatase-5 (PP5) that binds to its catalytic domain and causes apoptosis in renal cancer[1]. | | References | [1] Elham F Ahanin, et al. Catalytic inhibitor of Protein Phosphatase 5 activates the extrinsic apoptotic pathway by disrupting complex II in kidney cancer. Cell Chem Biol. 2023 Oct 19;30(10):1223-1234.e12. DOI:10.1016/j.chembiol.2023.06.026 |
| | PP5-IN-1 Preparation Products And Raw materials |
|