- 1-HYDROXYMETHYL-3-CYCLOPENTENE
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- $101.00 / 1KG
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2025-09-25
- CAS:25125-21-7
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: g-kg-tons, free sample is available
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| | 1-HYDROXYMETHYL-3-CYCLOPENTENE Basic information |
| Product Name: | 1-HYDROXYMETHYL-3-CYCLOPENTENE | | Synonyms: | 1-HYDROXYMETHYL-3-CYCLOPENTENE;Cyclopent-3-enyl-methanol;3-Cyclopenten-1-ylMethanol;cyclopent-3-en-1-ylMethanol;3-Cyclopentene-1-Methanol;Cyclopent-3-ene-1-methanol;1-HYDROXYMETHYL-3-CYCLOPENTENE ISO 9001：2015 REACH;3-Cyclopentene-1-methanol (7CI, 8CI, 9CI, ACI) | | CAS: | 25125-21-7 | | MF: | C6H10O | | MW: | 98.14 | | EINECS: | | | Product Categories: | pharmacetical | | Mol File: | 25125-21-7.mol |  |
| | 1-HYDROXYMETHYL-3-CYCLOPENTENE Chemical Properties |
| Boiling point | 105-108 °C | | density | 0.975±0.06 g/cm3(Predicted) | | storage temp. | 2-8°C | | pka | 14.93±0.10(Predicted) | | Appearance | Colorless to light yellow Liquid |
| Hazard Codes | Xn | | Risk Statements | 11-22 | | Safety Statements | 9-16-33 | | RIDADR | 1993 | | HazardClass | 3 | | PackingGroup | Ⅲ |
| | 1-HYDROXYMETHYL-3-CYCLOPENTENE Usage And Synthesis |
| Synthesis | General procedure for the synthesis of 1-hydroxymethyl-3-cyclopentene from 3-cyclopentenecarboxylic acid: (a) To an anhydrous tetrahydrofuran (100 ml) suspension of lithium aluminium hydride (0.5083 g, 13.37 mmol, 3 eq.), a solution of 3-cyclopentenecarboxylic acid (0.5000 g, 4.45 mmol) was slowly added dropwise at -78°C for a controlled duration of 1 hours. The reaction mixture was stirred continuously at this temperature for 6 h. The reaction was subsequently quenched with 15 ml of 1 M NaOH solution. After continued stirring for 2 h, the reaction mixture was concentrated, washed with ether and dried with anhydrous magnesium sulfate to give the final clarified liquid product cyclopent-3-enylmethanol (3.79 mmol, molecular weight 98.14 g/mol, 85% yield). The product was characterized by 1H NMR (300 MHz, CDCl3): δ 2.12-2.16 (tttt, 1H), 2.49-2.53 (dd, 2H), 3.57-3.58 (d, 3H, J=5.14 Hz), 5.69 (s, 2H). | | References | [1] Tetrahedron, 2003, vol. 59, # 5, p. 671 - 676
[2] Journal of the American Chemical Society, 1982, vol. 104, p. 7105
[3] Journal of the Chemical Society, Perkin Transactions 1, 2000, # 14, p. 2175 - 2178
[4] European Journal of Organic Chemistry, 2004, # 2, p. 289 - 303
[5] Journal of Heterocyclic Chemistry, 1989, vol. 26, # 2, p. 451 - 452 |
| | 1-HYDROXYMETHYL-3-CYCLOPENTENE Preparation Products And Raw materials |
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