Oxyphenonium

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Oxyphenonium Basic information
Product Name:Oxyphenonium
Synonyms:Diethylmethyl[2-(hydroxyphenylcyclohexylacetoxy)ethyl]aminium;Ethanaminium, 2-[(2-cyclohexyl-2-hydroxy-2-phenylacetyl)oxy]-N,N-diethyl-N-methyl-;Oxyphenonium free base;2-[Cyclohexyl(hydroxy)(phenyl)acetoxy]-N,N-diethyl-N-methylethanaminium
CAS:14214-84-7
MF:C21H34NO3
MW:348.5
EINECS:
Product Categories:
Mol File:14214-84-7.mol
Oxyphenonium Structure
Oxyphenonium Chemical Properties
Safety Information
MSDS Information
Oxyphenonium Usage And Synthesis
OriginatorA-Spasm ,Acme Laboratories Ltd.
DefinitionChEBI: 2-(2-cyclohexyl-2-hydroxy-1-oxo-2-phenylethoxy)ethyl-diethyl-methylammonium is an acylcholine.
Manufacturing Process1 mol cycloxehylhydroxyphenylacetic acid methyl ester was mixed with 1 mol 2-diethylaminoethanol in presence of 1 mol sodium methylate to give cycloxehylhydroxyphenylacetic acid 2-diethylamino-ethyl ester.
5 parts by weight of it was dissolved in 50 volumes glacial acetic acid and a gaseous methyl bromide was introduced. The mixture was heated to about 50°C and crystallization of cycloxehylhydroxyphenylacetic acid diethylaminoethyl ester methyl bromide has shortly after begun. On cooling the crystals was filtered off and recrystallized from mixture of ethyl acetate ant a little ethanol to give the oxyphenonium bromide. MP: 189°-191°C.
Brand nameAntrenyl (Novartis).
Therapeutic FunctionAnticholinergic, Spasmolytic
Oxyphenonium Preparation Products And Raw materials
Raw materialsMethyl bromide-->Diethylaminoethanol
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