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| | NSC80734 Basic information |
| Product Name: | NSC80734 | | Synonyms: | NSC80734;Urea, N,N′′-(oxydi-4,1-phenylene)bis[N′-(4-cyanophenyl)- | | CAS: | 501950-47-6 | | MF: | C28H20N6O3 | | MW: | 488.5 | | EINECS: | | | Product Categories: | | | Mol File: | 501950-47-6.mol |  |
| | NSC80734 Chemical Properties |
| Boiling point | 574.309±50.00 °C(Press: 760.00 Torr)(predicted) | | density | 1.399±0.10 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | | pka | 13.137±0.70(predicted) | | form | Solid | | color | White to off-white |
| | NSC80734 Usage And Synthesis |
| Uses | NSC80734 is a IL- 18 inhibitor. NSC80734 disrupts hIL-18 binding to the ectromelia virus IL-18BP. NSC80734 inhibits IL-18-induced production of IFN-γ[1]. | | References | [1] Krumm B, et al. Identification of small molecule inhibitors of Interleukin-18. Sci Rep. 2017 Mar 28;7(1):483. DOI:10.1038/s41598-017-00532-x |
| | NSC80734 Preparation Products And Raw materials |
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