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| Product Name: | RAT TNF-ALPHA | | Synonyms: | RAT DIF;RAT DIFFERENTIATION-INDUCING FACTOR;RAT CACHECTIN;RAT TNF-A;RAT TNF-ALPHA;RAT TNFSF2;TUMOR NECROSIS FACTOR-ALPHA, RAT;TUMOR NECROSIS FACTOR-A RAT | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![RAT TNF-ALPHA Structure]() |
| | RAT TNF-ALPHA Chemical Properties |
| storage temp. | −20°C | | form | powder |
| | RAT TNF-ALPHA Usage And Synthesis |
| Description | Tumor Necrosis Factor-a Rat Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 157 amino acids and having a molecular mass of 17339.44 Dalton. The TNF-alpha is purified by standard chromatographic techniques. | | Source | Escherichia Coli | | Background | Tumor necrosis factor is a cytokine involved in systemic inflammation and is a member of a group of cytokines that all stimulate the acute phase reaction. TNF is mainly secreted by macrophages.
TNF causes apoptotic cell death, cellular proliferation, differentiation, inflammation, tumorigenesis and viral replication, TNF is also involved in lipid metabolism, and coagulation. TNF's primary role is in the regulation of immune cells.
Dysregulation and, in particular, overproduction of TNF have been implicated in a variety of human diseases- autoimmune diseases, and cancer. |
| | RAT TNF-ALPHA Preparation Products And Raw materials |
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