Acetamide, 2-[(4-bromo-3-methylphenyl)amino]-N-ethyl-

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Acetamide, 2-[(4-bromo-3-methylphenyl)amino]-N-ethyl- Suppliers list
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
Company Name: Shaoguan Qicheng Biotechnology Co., Ltd  
Tel: 18122215013
Email: 780229652@qq.com
Company Name: Zhejiang Huida Biotech Co., Ltd.  
Tel: 0571-89903022 18679456698
Email: zilong@hizyme.com
Acetamide, 2-[(4-bromo-3-methylphenyl)amino]-N-ethyl- Basic information
Product Name:Acetamide, 2-[(4-bromo-3-methylphenyl)amino]-N-ethyl-
Synonyms:Acetamide, 2-[(4-bromo-3-methylphenyl)amino]-N-ethyl-;JX237
CAS:1021125-90-5
MF:C11H15BrN2O
MW:271.15
EINECS:
Product Categories:
Mol File:1021125-90-5.mol
Acetamide, 2-[(4-bromo-3-methylphenyl)amino]-N-ethyl- Structure
Acetamide, 2-[(4-bromo-3-methylphenyl)amino]-N-ethyl- Chemical Properties
Boiling point 455.6±40.0 °C(predicted)
density 1.377±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
pka15.55±0.46(predicted)
form Solid
color Yellow to brown
Safety Information
MSDS Information
Acetamide, 2-[(4-bromo-3-methylphenyl)amino]-N-ethyl- Usage And Synthesis
UsesJX237 is an inhibitor of the epithelial neutral amino acid transporter B0AT1 (SLC6A19) with an IC50 value of 31 nM. JX237 is the main transporter for the absorption of neutral amino acids in the intestines and their reabsorption in the kidneys. By inhibiting B0AT1, JX237 can help normalize elevated plasma amino acids in rare amino acid metabolic disorders like phenylketonuria and urea cycle disorders[1].
References[1] Xu J, et al. Molecular basis of inhibition of the amino acid transporter B0AT1 (SLC6A19). Nat Commun. 2024 Aug 22;15(1):7224. DOI:10.1038/s41467-024-51748-1
Acetamide, 2-[(4-bromo-3-methylphenyl)amino]-N-ethyl- Preparation Products And Raw materials
Tag:Acetamide, 2-[(4-bromo-3-methylphenyl)amino]-N-ethyl-(1021125-90-5) Related Product Information
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