3H-Pyrrolo[3,4-c]pyridin-3-one, 7-(7-fluoroimidazo[1,2-a]pyridin-3-yl)-1,2-dihydro-4-[[4-[(3S)-3-(1-hydroxy-1-methylethyl)-1-piperidinyl]phenyl]amino]-

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3H-Pyrrolo[3,4-c]pyridin-3-one, 7-(7-fluoroimidazo[1,2-a]pyridin-3-yl)-1,2-dihydro-4-[[4-[(3S)-3-(1-hydroxy-1-methylethyl)-1-piperidinyl]phenyl]amino]- Basic information
Product Name:3H-Pyrrolo[3,4-c]pyridin-3-one, 7-(7-fluoroimidazo[1,2-a]pyridin-3-yl)-1,2-dihydro-4-[[4-[(3S)-3-(1-hydroxy-1-methylethyl)-1-piperidinyl]phenyl]amino]-
Synonyms:3H-Pyrrolo[3,4-c]pyridin-3-one, 7-(7-fluoroimidazo[1,2-a]pyridin-3-yl)-1,2-dihydro-4-[[4-[(3S)-3-(1-hydroxy-1-methylethyl)-1-piperidinyl]phenyl]amino]-;HPK1-IN-49
CAS:2845144-97-8
MF:C28H29FN6O2
MW:500.57
EINECS:
Product Categories:
Mol File:2845144-97-8.mol
3H-Pyrrolo[3,4-c]pyridin-3-one, 7-(7-fluoroimidazo[1,2-a]pyridin-3-yl)-1,2-dihydro-4-[[4-[(3S)-3-(1-hydroxy-1-methylethyl)-1-piperidinyl]phenyl]amino]- Structure
3H-Pyrrolo[3,4-c]pyridin-3-one, 7-(7-fluoroimidazo[1,2-a]pyridin-3-yl)-1,2-dihydro-4-[[4-[(3S)-3-(1-hydroxy-1-methylethyl)-1-piperidinyl]phenyl]amino]- Chemical Properties
density 1.41±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
pka12.08±0.20(predicted)
Safety Information
MSDS Information
3H-Pyrrolo[3,4-c]pyridin-3-one, 7-(7-fluoroimidazo[1,2-a]pyridin-3-yl)-1,2-dihydro-4-[[4-[(3S)-3-(1-hydroxy-1-methylethyl)-1-piperidinyl]phenyl]amino]- Usage And Synthesis
UsesHPK1-IN-49 (Compound I-4) is an inhibitor for hematopoietic progenitor kinase 1 (HPK1) with an IC50 >100 nM[1].
IC 50HPK1
References[1] Kaila N, et al., SUBSTITUTED PYRROLO[3,4-c]PYRIDINES AS HPK1 ANTAGONISTS. US20240190895.
3H-Pyrrolo[3,4-c]pyridin-3-one, 7-(7-fluoroimidazo[1,2-a]pyridin-3-yl)-1,2-dihydro-4-[[4-[(3S)-3-(1-hydroxy-1-methylethyl)-1-piperidinyl]phenyl]amino]- Preparation Products And Raw materials
Tag:3H-Pyrrolo[3,4-c]pyridin-3-one, 7-(7-fluoroimidazo[1,2-a]pyridin-3-yl)-1,2-dihydro-4-[[4-[(3S)-3-(1-hydroxy-1-methylethyl)-1-piperidinyl]phenyl]amino]-(2845144-97-8) Related Product Information
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