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| | 14α-Demethylase-IN-1 Basic information |
| | 14α-Demethylase-IN-1 Chemical Properties |
| Boiling point | 540.0±60.0 °C(predicted) | | density | 1.23±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted) | | pka | 7.22±0.10(predicted) |
| | 14α-Demethylase-IN-1 Usage And Synthesis |
| Uses | 14α-Demethylase-IN-1 (compound 2e) is a 14α-demethylase inhibitor and can be used as an antifungal agent. 14α-Demethylase-IN-1 (48 h) exhibits MIC50 values of 2.47 μM, 1.23 μM, 19.70 μM, and 19.70 μM for C. albicans, C. parapsilosis, C. krusei, and C. glabrata, respectively[1]. | | References | [1] Sazan Haji Ali, et al. Design, Synthesis, Investigation, and Biological Activity Assessments of (4-Substituted-Phenyl)- N-(3-morpholinopropyl)-3-phenylthiazol-2(3 H)-imine Derivatives as Antifungal Agents. ACS Omega. 2024 Sep 16;9(38):39326-39343. DOI:10.1021/acsomega.3c07879 |
| | 14α-Demethylase-IN-1 Preparation Products And Raw materials |
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