Antibacterial agent 229

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Antibacterial agent 229 Suppliers list
Company Name: TargetMol  
Tel: 400-821-0310 15002144251
Email: xuexiang.shao@tsbiochem.com
Antibacterial agent 229 Basic information
Product Name:Antibacterial agent 229
Synonyms:Antibacterial agent 229;Hydrazinecarbothioamide, 2-[2-[3-(2-amino-4-thiazolyl)-7-chloro-6-fluoro-4-oxo-1(4H)-quinolinyl]-1-methylethylidene]-
CAS:3049500-54-8
MF:C16H14ClFN6OS2
MW:424.91
EINECS:
Product Categories:
Mol File:3049500-54-8.mol
Antibacterial agent 229 Structure
Antibacterial agent 229 Chemical Properties
Boiling point 681.5±65.0 °C(predicted)
density 1.66±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
pka11.27±0.70(predicted)
Safety Information
MSDS Information
Antibacterial agent 229 Usage And Synthesis
UsesAntibacterial agent 229 (compound 8a) is a potent antibacterial agent. Antibacterial agent 229 shows antibacterial and antifungal abilities. Antibacterial agent 229 disrupts the integrity of the bacterial membrane, intercalates into DNA. Antibacterial agent 229 inhibits topoisomerase IV with an IC50 value of 10.88 μM[1].
IC 50TOPO IV: 10.88 μM (IC50)
References[1] Zang ZL, et al. Synthesis and antibacterial medicinal evaluation of carbothioamido hydrazonyl thiazolylquinolone with multitargeting antimicrobial potential to combat increasingly global resistance. Eur J Med Chem. 2024 Sep 5;275:116626. DOI:10.1016/j.ejmech.2024.116626
Antibacterial agent 229 Preparation Products And Raw materials
Tag:Antibacterial agent 229(3049500-54-8) Related Product Information
TOP2A Protein, Human