| Company Name: |
J & K SCIENTIFIC LTD.
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18210857532; 18210857532 |
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jkinfo@jkchemical.com |
| Products Intro: |
Product Name:Diethyl isocyanoMethylphosphonate
CAS:41003-94-5
Purity:97% Package:1ML,5ML
|
| Company Name: |
Energy Chemical
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| Tel: |
021-021-58432009 400-005-6266 |
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sales8178@energy-chemical.com |
| Products Intro: |
Product Name:DIETHYL ISOCYANOMETHYLPHOSPHONATE
CAS:41003-94-5
Purity:97% Package:1ML
|
| Company Name: |
Shanghai Hanhong Scientific Co.,Ltd.
|
| Tel: |
021-54306202 13764082696 |
| Email: |
info@hanhongsci.com |
| Products Intro: |
Product Name:Diethyl isocyanomethylphosphonate
CAS:41003-94-5
Purity:98% Remarks:SR01010097
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| | DIETHYL ISOCYANOMETHYLPHOSPHONATE Basic information |
| Product Name: | DIETHYL ISOCYANOMETHYLPHOSPHONATE | | Synonyms: | [(Diethoxyphosphinyl)methyl] isocyanide;Diethoxyphosphinylmethyl isocyanide;Diethyl isocyanomethylphosphonate,97%;DIETHYL ISOCYANOMETHYLPHOSPHONATE;ISOCYANOMETHYL-PHOSPHONIC ACID DIETHYL ESTER;ISOCYANOMETHYLPHOSPHONONIC ACID DIETHYL ESTER;Diethyl isocyanomethylphosphonate 97%;Diethyl (isocyanomethyl) | | CAS: | 41003-94-5 | | MF: | C6H12NO3P | | MW: | 177.14 | | EINECS: | | | Product Categories: | | | Mol File: | 41003-94-5.mol |  |
| | DIETHYL ISOCYANOMETHYLPHOSPHONATE Chemical Properties |
| Boiling point | 84-87 °C0.1 mm Hg(lit.) | | density | 1.105 g/mL at 25 °C(lit.) | | refractive index | n20/D 1.433(lit.) | | Fp | >230 °F | | storage temp. | 2-8°C | | form | Liquid | | color | Clear colorless to yellow | | BRN | 4674920 | | InChI | 1S/C6H12NO3P/c1-4-9-11(8,6-7-3)10-5-2/h4-6H2,1-2H3 | | InChIKey | ICURVXBGGDVHDT-UHFFFAOYSA-N | | SMILES | CCOP(=O)(C[N+]#[C-])OCC | | CAS DataBase Reference | 41003-94-5 |
| Hazard Codes | Xi,Xn | | Risk Statements | 36/37/38-20/21/22 | | Safety Statements | 26-36 | | RIDADR | UN2206 | | WGK Germany | 3 | | F | 8-9 | | HazardClass | 6.1 | | HS Code | 29319090 | | Storage Class | 10 - Combustible liquids | | Hazard Classifications | Acute Tox. 4 Dermal
Acute Tox. 4 Inhalation
Acute Tox. 4 Oral
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| | DIETHYL ISOCYANOMETHYLPHOSPHONATE Usage And Synthesis |
| Description | Diethyl isocyanoMethylphosphonate is a reagent for the elongation of aldehydes and ketones with a one-carbon unit; connective reagent; N,P-acetals; reagent for the conversion of nitroalkenes into 2-pyrrolephosphonates. | | Chemical Properties | Clear colorless to yellow liquid | | Uses | Reactant for:
- Copper-catalyzed cycloaddition reactions
- Preparation of orally bioavailable diamide prodrugs that lower glucose in diabetic animals through inhibition of fructose-1,6-bisphosphatase
- Synthesis of sterol analogs as antifungal agents against plant pathogens
- Asymmetric synthesis of steroidal 2,5-diketopiperazines prepared via isocyanide chemistry based on stereoselective Ugi four component condensation and subsequent cyclocondensation reactions
- The Passerini reaction
| | reaction suitability | reaction type: C-C Bond Formation | | Synthesis | Diethyl isocyanoMethylphosphonate is prepared by dehydration of N-(diethoxyphosphorylmethyl)formamide. | | storage | Stored for long periods of time at 0 °C or below |
| | DIETHYL ISOCYANOMETHYLPHOSPHONATE Preparation Products And Raw materials |
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