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| | 2-Chloropyridine-5-boronic acid Basic information |
| | 2-Chloropyridine-5-boronic acid Chemical Properties |
| Melting point | 165 °C(lit.) | | Boiling point | 336.9±52.0 °C(Predicted) | | density | 1.41±0.1 g/cm3(Predicted) | | storage temp. | Keep in dark place,Sealed in dry,Room Temperature | | solubility | soluble in Methanol | | form | powder to crystal | | pka | 6.70±0.10(Predicted) | | color | White to Light yellow | | BRN | 9119810 | | InChI | 1S/C5H5BClNO2/c7-5-2-1-4(3-8-5)6(9)10/h1-3,9-10H | | InChIKey | WPAPNCXMYWRTTL-UHFFFAOYSA-N | | SMILES | OB(O)c1ccc(Cl)nc1 | | CAS DataBase Reference | 444120-91-6(CAS DataBase Reference) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38-22 | | Safety Statements | 26-36/37-36/37/39 | | WGK Germany | 3 | | HazardClass | IRRITANT | | HS Code | 29349990 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| | 2-Chloropyridine-5-boronic acid Usage And Synthesis |
| Chemical Properties | White to off-white solid | | Uses | 6-Chloro-3-pyridinylboronic acid can be used:
- To prepare biologically significant 3-arylcoumarins by reacting with 3-chlorocoumarin through Suzuki reaction.
- As a substrate in the synthesis of 11-(pyridinylphenyl)steroid with progesterone agonist/antagonist profile.
- As a substrate in the preparation of α- secondary and tertiary pyridines by the reaction of pyridotriazoles with boronic acids.
- As a substrate in the palladium-catalyzed α-arylation of saturated cyclic amines and N-methyl amines.
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| | 2-Chloropyridine-5-boronic acid Preparation Products And Raw materials |
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