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| | 1-cinnamoylpyrrolidine Basic information |
| Product Name: | 1-cinnamoylpyrrolidine | | Synonyms: | 1-cinnamoylpyrrolidine;1-[(2E)-1-Oxo-3-phenyl-2-propenyl]pyrrolidine;Cinnamopyrrolidide;2-Propen-1-one, 3-phenyl-1-(1-pyrrolidinyl)-, (2E)-;3-Phenyl-1-(pyrrolidin-1-yl)prop-2-en-1-one;1-Cinnamoylpyrrolidine, 10 mM in DMSO;3-PHENYL-1-PYRROLIDIN-1-YL-PROPENONE | | CAS: | 52438-21-8 | | MF: | C13H15NO | | MW: | 201.26 | | EINECS: | | | Product Categories: | Alkaloids | | Mol File: | 52438-21-8.mol |  |
| | 1-cinnamoylpyrrolidine Chemical Properties |
| Melting point | 123℃ | | storage temp. | Store at -20°C | | solubility | Acetone: soluble; Chloroform: soluble; Dichloromethane: soluble; DMSO: soluble; Ethyl Acetate: soluble | | form | A solid |
| | 1-cinnamoylpyrrolidine Usage And Synthesis |
| Uses | 1-Cinnamoylpyrrolidine (Compound 3), a crude extract prepared from Piper caninum, is a DNA strand scission agent, induces the relaxation of supercoiled pBR322 plasmid DNA[1].
1-Cinnamoylpyrrolidine (Compound 4) inhibits platelet aggregation induced by PAF with an IC50 of 37.3 μM[2]. | | Definition | ChEBI: 1-Cinnamoylpyrrolidine is an olefinic compound. It is functionally related to a cinnamic acid. | | References | [1] Send toBioorg Med Chem.Ma J, et al. Phenolic acid amides: a new type of DNA strand scission agent from Piper caninum. Bioorg Med Chem. 2004 Jul 15;12(14):3885-9. DOI:10.1016/j.bmc.2004.05.007
[2] Chen IS, et al. Amides with anti-platelet aggregation activity from Piper taiwanense. Fitoterapia. 2007 Sep;78(6):414-9. Epub 2007 May 24. DOI:10.1016/j.fitote.2007.04.009 |
| | 1-cinnamoylpyrrolidine Preparation Products And Raw materials |
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