- XPhos Pd G1
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- $1.00 / 1KG
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2020-04-22
- CAS:1028206-56-5
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 20T
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| Product Name: | XPhos Pd G1 | | Synonyms: | XPhos Palladacycle;XPhos precatalyst;[2-(2-AMinoethyl)phenyl](chloro)palladiuM-dicyclohexyl(2',4',6'-triisopropyl-2-biphenylyl)phosphine (1:1);Chloro(2-dicyclohexylphosphino-2',4',6'-tri-i-propyl-1,1'-biphenyl)[2-(2-aminoethyl)phenyl]palladium(II) ;XPhos Pd G1;Chloro(2-dicyclohexylphosphino-2',4',6'-tri-i-propyl-1,1'-biphenyl)[2-(2-aminoethyl)phenyl] palladium(II) methyl-t-butylether adduct;XPhos Pd;Chloro(2-dicyclohexylphosphino-2',4',6'-tri-i-propyl-1,1'-biphenyl)[2-(2-aminoethyl)phenyl] palladium(II) methyl-t-butylether adduct, min. 98% [XPhos Palladacycle Gen. 1] | | CAS: | 1028206-56-5 | | MF: | C41H59ClNPPd | | MW: | 738.77 | | EINECS: | 633-034-5 | | Product Categories: | Buchwald Ligands&Precatalysts;Buchwald Precatalysts Series;Pd | | Mol File: | 1028206-56-5.mol |  |
| | XPhos Pd G1 Chemical Properties |
| Melting point | 205-210°C | | form | Powder | | color | white | | CAS DataBase Reference | 1028206-56-5 |
| | XPhos Pd G1 Usage And Synthesis |
| Reaction |
- Catalyst for cross-coupling reactions of electron-deficient anilines with aryl chlorides.
- Catalyst for rapid C-N bond-forming process at low catalyst loading.
- Catalyst for C-N cross-coupling reactions, at or below room temperature.
- Catalyst for the synthesis of tetracyclic indoles via intermolecular α-arylation of ketones.
- Catalyst for the cross-coupling of benzyl chlorides with cyclopropanol-derived ketone homoenolates
| | Uses | XPhos Pd G1 is used as androgen receptor modulator for treatment of disorders including prostate cancer. | | Uses | Application Guide for Palladium Catalyzed Cross-Coupling Reactions
Catalyst used for:
- Amination / cyclization reactions
- C-N bond-forming reactions via packed-bed microreactors
- Boration of aryl chlorides
- Arylation of oxazole
- Cross-coupling reactions
| | Preparation | XPhos Pd G1 is an insoluble solid that can be prepared by cross-coupling reactions of imidazole derivatives with dioxane. | | General Description | Material may contain up to 5% pentane | | reaction suitability | core: palladium
reaction type: Buchwald-Hartwig Cross Coupling Reaction
reaction type: Heck Reaction
reaction type: Hiyama Coupling
reaction type: Negishi Coupling
reaction type: Sonogashira Coupling
reaction type: Stille Coupling
reaction type: Suzuki-Miyaura Coupling
reagent type: catalyst
reaction type: Cross Couplings | | Physiological effects | XPhos Pd G1 has been shown to have anti-infectious properties against bacteria and viruses including influenza A, respiratory syncytial virus (RSV), human immunodeficiency virus (HIV), and hepatitis B. It also has metabolic effects on the body by reducing levels of pyridine compounds and increasing pyrazolyl concentrations in the blood stream. |
| | XPhos Pd G1 Preparation Products And Raw materials |
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