4-Ethylphenylamino-1,2-dimethyl-6-methylaminopyrimidinium chloride

4-Ethylphenylamino-1,2-dimethyl-6-methylaminopyrimidinium chloride Suppliers list

Company Name:	3B Pharmachem (Wuhan) International Co.,Ltd.
Tel:	18930552037
Email:	3bsc@sina.com

Company Name:	Energy Chemical
Tel:	400-0056266
Email:	marketing1@energy-chemical.com

4-Ethylphenylamino-1,2-dimethyl-6-methylaminopyrimidinium chloride Basic information

Product Name:	4-Ethylphenylamino-1,2-dimethyl-6-methylaminopyrimidinium chloride
Synonyms:	ZD 7288;N-Ethyl-1,6-dihydro-1,2-dimethyl-6-(methylimino)-N-phenyl-4-Pyrimidinamine;ZD7288 hydrate;4-(N-Ethyl-N-phenylamino)-1,2 dimethyl-6-(methylamino) pyrimidinium chloride;4-Pyrimidinamine, N-ethyl-1,6-dihydro-1,2-dimethyl-6-(methylimino)-N-phenyl-;ZD7288 hydrate >=98% (HPLC);4-Ethylphenylamino-1,2-dimethyl-6-methylaminopyrimidinium chloride
CAS:	133060-80-7
MF:	C15H20N4
MW:	256.35
EINECS:
Product Categories:	Ion transporter and other ion channel
Mol File:	133060-80-7.mol

4-Ethylphenylamino-1,2-dimethyl-6-methylaminopyrimidinium chloride Chemical Properties

Boiling point	359.9±52.0 °C(Predicted)
density	1.04±0.1 g/cm3(Predicted)
storage temp.	2-8°C
solubility	DMSO: soluble10mg/mL, clear
pka	11.97±0.70(Predicted)
form	powder
color	white to beige
InChI	1S/C15H20N4.ClH.H2O/c1-5-19(13-9-7-6-8-10-13)15-11-14(16-3)18(4)12(2)17-15;;/h6-11H,5H2,1-4H3;1H;1H2/b16-14+;;
InChIKey	NCEDDDWQLCMZQG-UPONXUSQSA-N
SMILES	O.Cl.CCN(c1ccccc1)C2=CC(=N/C)\N(C)C(C)=N2

Safety Information

WGK Germany	3
Storage Class	11 - Combustible Solids

MSDS Information

4-Ethylphenylamino-1,2-dimethyl-6-methylaminopyrimidinium chloride Usage And Synthesis

Uses	ZD7288 hydrate has been used asI_hblocker to study its effect on neocortical tissue. It has been used as hyperpolarization-activated and cyclic nucleotide-gated (HCN)-channel blocker to test the involvement of HCN channels in the phototransduction pathway.
Biochem/physiol Actions	Selective blocker of cation channel Ih; If blocker and sino-atrial node function modulator, blocks hyperpolarization-activated and cyclic nucleotide-gated (HCN) channels.

4-Ethylphenylamino-1,2-dimethyl-6-methylaminopyrimidinium chloride Preparation Products And Raw materials

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