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Dimethyl 4-(2-Chlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate

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CAS:43067-01-2
Dimethyl 4-(2-Chlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate Basic information
Product Name:Dimethyl 4-(2-Chlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
Synonyms:Dimethyl 4-(2-Chlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate;4-(2-Chlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic acid dimethyl ester;4-(2-Chlorophenyl)-1,4-dihydro-2,6-diMethyl-3,5-pyridinedicarboxylic Acid 3,5-DiMethyl Ester;4-(2-Chlorophenyl)-3,5-di(Methoxycarbonyl)-2,6-diMethyl-1,4- dihydropyridine;AMlodipine IMpurity G (EP);AMlodipine EP IMpurity G;dimethyl 4-(2-chlorophenyl);Amlodipine Besylate Impurity G
CAS:43067-01-2
MF:C17H18ClNO4
MW:335.78
EINECS:
Product Categories:Aromatics;Heterocycles;Intermediates;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File:43067-01-2.mol
Dimethyl 4-(2-Chlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate Structure
Dimethyl 4-(2-Chlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate Chemical Properties
Melting point 196-198℃
Boiling point 436.7±45.0 °C(Predicted)
density 1.232±0.06 g/cm3(Predicted)
storage temp. Refrigerator
solubility Chloroform (Slightly), Dichloromethane (Slightly), DMSO (Slightly)
form Solid
pka2.79±0.70(Predicted)
color Off-White to Pale Yellow
Major Applicationpharmaceutical (small molecule)
InChI1S/C17H18ClNO4/c1-9-13(16(20)22-3)15(11-7-5-6-8-12(11)18)14(10(2)19-9)17(21)23-4/h5-8,15,19H,1-4H3
InChIKeyREIGLQUFMMOAFU-UHFFFAOYSA-N
SMILESO=C(OC)C1=C(C)NC(C)=C(C(OC)=O)C1C2=C(Cl)C=CC=C2
Safety Information
WGK Germany WGK 3
HS Code 2933399090
Storage Class11 - Combustible Solids
Hazard ClassificationsAcute Tox. 4 Oral
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
MSDS Information
Dimethyl 4-(2-Chlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate Usage And Synthesis
UsesAmlodipine Besilate (A633500) impurity.
UsesDimethyl 4-(2-Chlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate (Amlodipine EP Impurity G) is an Amlodipine Besilate (A633500) impurity.
Dimethyl 4-(2-Chlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate Preparation Products And Raw materials
Tag:Dimethyl 4-(2-Chlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate(43067-01-2) Related Product Information
4-chloro-3-oxobutyric acid Dehydro AMlodipine Oxalate diethyl 2,6-bis((2-aminoethoxy)methyl)-4-(2-chlorophenyl)-1,4-dihydropyridine-3,5-dicarboxylate Bis(aminoethoxy) Amlodipine N-[2-[(Methylamino)carbonyl]benzoyl] Amlodipine Dimethyl Ester Amlodipine EP Impurity D AMlodipine Metabolite 5 2-Carboxybenzoyl Amlodipine O-Des[2-aMinoethyl]-O-carboxyMethyl-dehydroaMlodipine Amlodipine N-Lactoside Amlodipine N-Glucose Phthaloyl amlodipine d-Amlodipine Amlodipine Impurity 48 Amlodipine N-Galactose Amlodipine Impurity 10 Amlodipine iMpurity K