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| | Ac-Ile-Glu-Thr-Asp-AMC Basic information |
| Product Name: | Ac-Ile-Glu-Thr-Asp-AMC | | Synonyms: | N-Acetyl-L-isoleucyl-L-α-glutamyl-L-threonyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-α-asparagine;N-Acetyl-L-isoleucyl-L-α-glutamyl-L-threonyl-N-(4-methyl-2-oxo-2H-chromen-7-yl)-L-α-asparagine;L-α-Asparagine, N-acetyl-L-isoleucyl-L-α-glutamyl-L-threonyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-;Ac-Ile-Glu-Thr-Asp-MCA [Ac-IETD-MCA] (5 mg vial);Caspase-3 Precursor Prote、Caspase 8 Substrate 1m, fluorogenic | | CAS: | 348079-17-4 | | MF: | C31H41N5O12 | | MW: | 675.69 | | EINECS: | | | Product Categories: | | | Mol File: | 348079-17-4.mol |  |
| | Ac-Ile-Glu-Thr-Asp-AMC Chemical Properties |
| Boiling point | 1157.6±65.0 °C(Predicted) | | density | 1.366±0.06 g/cm3(Predicted) | | pka | 4.09±0.10(Predicted) |
| | Ac-Ile-Glu-Thr-Asp-AMC Usage And Synthesis |
| Uses | Ac-IETD-AMC is a fluorogenic caspase-8/granzyme B substrate containing the acetyl (Ac) moiety. Ac-IETD-AMC is frequently used to measure caspase-8 activity[1]. | | References | [1] V Frost, et al. Exploitation of a non-apoptotic caspase to regulate the abundance of the cdkI p27(KIP1) in transformed lymphoid cells. Oncogene. 2001 May 17;20(22):2737-48. DOI:10.1038/sj.onc.1204367 |
| | Ac-Ile-Glu-Thr-Asp-AMC Preparation Products And Raw materials |
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