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| | 3-Biphenylboronic acid pinacol ester Basic information |
| Product Name: | 3-Biphenylboronic acid pinacol ester | | Synonyms: | 3-Biphenylboronic acid pinacol ester;1,3,2-Dioxaborolane,2-[1,1'-biphenyl]-3-yl-4,4,5,5-tetramethyl-;4,4,5,5-tetramethyl-2-(3-phenylphenyl)-1,3,2-dioxaborolane;-biphenyl]-3-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane;Biphenyl-3-boronic Acid Pinacol Ester;3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)biphenyl;1,1`-BIPHENYL]-3-YLBORONIC ACID PINACOL ESTER;[1,1'-Biphenyl]-3-boronic acid pinacol ester | | CAS: | 912844-88-3 | | MF: | C18H21BO2 | | MW: | 280.17 | | EINECS: | | | Product Categories: | | | Mol File: | 912844-88-3.mol |  |
| | 3-Biphenylboronic acid pinacol ester Chemical Properties |
| Melting point | 82 °C | | Boiling point | 412.7±24.0 °C(Predicted) | | density | 1.05±0.1 g/cm3(Predicted) | | storage temp. | under inert gas (nitrogen or Argon) at 2-8°C | | form | powder to crystal | | color | White to Almost white | | CAS DataBase Reference | 912844-88-3 |
| | 3-Biphenylboronic acid pinacol ester Usage And Synthesis |
| Uses | suzuki reaction | | Synthesis | Synthesis Example 8: Synthesis of Intermediates I-8
3-Bromo-1,1 '-biphenyl (20 g, 85.8 mmol) was dissolved in dimethylformamide (DMF) (1 L) under nitrogen protection, and bis(pinacolato)diboron (26 g, 103 mmol), [1,1'-bis(diphenylphosphino)ferrocene]palladium(II) dichloride (0.7 g, 0.85 mmol), and potassium acetate (58 g 595 mmol). The reaction mixture was heated to 150 °C and refluxed for 5 hours. After completion of the reaction, water was added to the reaction solution, the mixture was filtered and dried in a vacuum oven. The resulting residue was separated and purified by fast column chromatography to afford the target compound I-8 (20 g, 85% yield).
High resolution mass spectrometry (HRMS, 70 eV, EI+): the calculated m/z value for C18H21B2O was 280.1635 and the measured value was 280.
Elemental analysis results: C, 77%; H, 7%. | | References | [1] Patent: US2017/331067, 2017, A1. Location in patent: Paragraph 0212-0215 |
| | 3-Biphenylboronic acid pinacol ester Preparation Products And Raw materials |
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