ChemicalBook > Product Catalog >Analytical Chemistry >Standard >Pharmaceutical Impurity Reference Standards >(1'R,3'S,3S,5R,6R)-5-AMINO-2-AMINOMETHYL-6-(4,6-DIAMINO-2,3-DIHYDROXY-CYCLOHEXYLOXY)-TETRAHYDRO-PYRAN-3,4-DIOL

(1'R,3'S,3S,5R,6R)-5-AMINO-2-AMINOMETHYL-6-(4,6-DIAMINO-2,3-DIHYDROXY-CYCLOHEXYLOXY)-TETRAHYDRO-PYRAN-3,4-DIOL

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(1'R,3'S,3S,5R,6R)-5-AMINO-2-AMINOMETHYL-6-(4,6-DIAMINO-2,3-DIHYDROXY-CYCLOHEXYLOXY)-TETRAHYDRO-PYRAN-3,4-DIOL Suppliers list
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Products Intro: Product Name:Neomycin Sulfate EP Impurity A
CAS:3947-65-7
Purity:0.99 Package:10mg;25mg;50mg;100mg
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Products Intro: Product Name:(1'R,3'S,3S,5R,6R)-5-AMINO-2-AMINOMETHYL-6-(4,6-DIAMINO-2,3-DIHYDROXY-CYCLOHEXYLOXY)-TETRAHYDRO-PYRAN-3,4-DIOL
CAS:3947-65-7
Purity:98% Package:1g,10g,25g,100g,500g,1kg
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Products Intro: Product Name:Neamine
CAS:3947-65-7
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Products Intro: Product Name:(2R,3S,4R,5R,6R)-5-Amino-2-(aminomethyl)-6-(((1R,2R,3S,4R,6S)-4,6-diamino-2,3-dihydroxycyclohexyl)oxy)tetrahydro-2H-pyran-3,4-diol
CAS:3947-65-7
Purity:NLT 98% Package:1G;100G;1KG;50KG Remarks:MC795080
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Products Intro: Product Name:Neamine
CAS:3947-65-7
Purity:98% Package:1KG|25KG Remarks:E-mail:1110@dideu.com

(1'R,3'S,3S,5R,6R)-5-AMINO-2-AMINOMETHYL-6-(4,6-DIAMINO-2,3-DIHYDROXY-CYCLOHEXYLOXY)-TETRAHYDRO-PYRAN-3,4-DIOL manufacturers

  • Neamine
  • Neamine pictures
  • 2026-06-30
  • CAS:3947-65-7
  • Purity: 98%
  • Supply Ability: 20Tons
(1'R,3'S,3S,5R,6R)-5-AMINO-2-AMINOMETHYL-6-(4,6-DIAMINO-2,3-DIHYDROXY-CYCLOHEXYLOXY)-TETRAHYDRO-PYRAN-3,4-DIOL Basic information
Product Name:(1'R,3'S,3S,5R,6R)-5-AMINO-2-AMINOMETHYL-6-(4,6-DIAMINO-2,3-DIHYDROXY-CYCLOHEXYLOXY)-TETRAHYDRO-PYRAN-3,4-DIOL
Synonyms:5-AMINO-2-AMINOMETHYL-6-(4,6-DIAMINO-2,3-DIHYDROXY-CYCLOHEXYLOXY)-TETRAHYDRO-PYRAN-3,4-DIOL;U-5214;2-deoxy-4-o-(2,6-diamino-2,6-dideoxy-alpha-d-glucopyranosyl)-d-streptamin;(1'R,3'S,3S,5R,6R)-5-AMINO-2-AMINOMETHYL-6-(4,6-DIAMINO-2,3-DIHYDROXY-CYCLOHEXYLOXY)-TETRAHYDRO-PYRAN-3,4-DIOL;5-amino-2-(aminomethyl)-6-(4,6-diamino-2,3-dihydroxycyclohexyl)oxyoxane-3,4-diol;dekamycinv;neamin;nebramycinx
CAS:3947-65-7
MF:C12H26N4O6
MW:322.36
EINECS:
Product Categories:Intermediates
Mol File:3947-65-7.mol
(1'R,3'S,3S,5R,6R)-5-AMINO-2-AMINOMETHYL-6-(4,6-DIAMINO-2,3-DIHYDROXY-CYCLOHEXYLOXY)-TETRAHYDRO-PYRAN-3,4-DIOL Structure
(1'R,3'S,3S,5R,6R)-5-AMINO-2-AMINOMETHYL-6-(4,6-DIAMINO-2,3-DIHYDROXY-CYCLOHEXYLOXY)-TETRAHYDRO-PYRAN-3,4-DIOL Chemical Properties
Melting point 225.5°C (rough estimate)
Boiling point 460.98°C (rough estimate)
alpha D25+112.8° (c = 1)
density 1.1885 (rough estimate)
refractive index 1.6120 (estimate)
storage temp. Hygroscopic, Refrigerator, Under inert atmosphere
solubility Aqueous Acid (Slightly), Methanol (Slightly, Heated), Water (Slightly)
pka13.24±0.70(Predicted)
form Solid
color White to Pale Yellow
Stability:Hygroscopic
Major Applicationpharmaceutical small molecule
InChIInChI=1/C12H26N4O6/c13-2-5-8(18)9(19)6(16)12(21-5)22-11-4(15)1-3(14)7(17)10(11)20/h3-12,17-20H,1-2,13-16H2/t3-,4+,5-,6-,7+,8-,9-,10-,11-,12-/s3
InChIKeySYJXFKPQNSDJLI-CLPOQDAFNA-N
SMILES[C@@H]1(O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O)[C@H]2O)[C@H](N)[C@@H](O)[C@H](O)[C@@H](CN)O1 |&1:0,2,3,6,8,10,12,14,16,18,r|
Safety Information
MSDS Information
(1'R,3'S,3S,5R,6R)-5-AMINO-2-AMINOMETHYL-6-(4,6-DIAMINO-2,3-DIHYDROXY-CYCLOHEXYLOXY)-TETRAHYDRO-PYRAN-3,4-DIOL Usage And Synthesis
UsesNeamine is normally found as a core structure of aminoglycoside antibiotics. It is used in the synthesis of disaccharide neamine derivatives as antibacterial agents.
DefinitionChEBI: 2-Deoxy-D-streptamine glycosylated at the 4-oxygen with a 6-amino-alpha-D-glucosaminyl group.
in vivo

Neamine (30-60 mg/kg; subcutaneous injection; daily; for 14 days; male Balb/c nude mice) has anti-tumor effects on AsPC-1 xenograft models. Neamine reduces the expression levels of ANG, Ki-67 and CD31 in tumor xenografts[1].

Animal Model:Male Balb/c nude mice (4 weeks old) injected with AsPC-1 cells[1]
Dosage:30 mg/kg, 60 mg/kg
Administration:Subcutaneous injection; daily; for 14 days
Result:Had anti-tumor effects on AsPC-1 xenograft models.
IC 50Aminoglycoside
(1'R,3'S,3S,5R,6R)-5-AMINO-2-AMINOMETHYL-6-(4,6-DIAMINO-2,3-DIHYDROXY-CYCLOHEXYLOXY)-TETRAHYDRO-PYRAN-3,4-DIOL Preparation Products And Raw materials
Tag:(1'R,3'S,3S,5R,6R)-5-AMINO-2-AMINOMETHYL-6-(4,6-DIAMINO-2,3-DIHYDROXY-CYCLOHEXYLOXY)-TETRAHYDRO-PYRAN-3,4-DIOL(3947-65-7) Related Product Information
Tobramycin Bekanamycin 2,6-DiaMino-2,3,6-trideoxy-D-ribo-Hexose Dihydrochloride 4-O-[6-Amino-2-[(aminocarbonyl)amino]-2,3,6-trideoxy-α-D-ribo-hexopyranosyl]-6-O-(3-amino-3-deoxy-α-D-glucopyranosyl)-2-deoxy-D-streptamine 3'-Deoxyneamine Tobramycin Impurity Neomycin sulfate impurity C (1'R,3'S,3S,5R,6R)-5-AMINO-2-AMINOMETHYL-6-(4,6-DIAMINO-2,3-DIHYDROXY-CYCLOHEXYLOXY)-TETRAHYDRO-PYRAN-3,4-DIOL Neomycin sulfate KANAMYCIN B SULFATE Naphazoline nitrate Neomycin RIBOSTAMYCIN SULFATE SALT NEAMINE HYDROCHLORIDE NEOMYCIN C SULFATE BUTIROSIN A 6-O-(2-Amino-2-deoxy-α-D-xylopyranosyl)-4-O-(2,6-diamino-2,6-dideoxy-α-D-glucopyranosyl)-2-deoxy-D-streptamine BUTIROSIN DISULPHATE