2-AMino-6-chloropurine -9-beta-D-(2'-deoxy-3',5'-di-O-benzoyl-2'-fluoro)arabinoriboside

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2-AMino-6-chloropurine -9-beta-D-(2'-deoxy-3',5'-di-O-benzoyl-2'-fluoro)arabinoriboside manufacturers
2-AMino-6-chloropurine -9-beta-D-(2'-deoxy-3',5'-di-O-benzoyl-2'-fluoro)arabinoriboside Basic information
Product Name:2-AMino-6-chloropurine -9-beta-D-(2'-deoxy-3',5'-di-O-benzoyl-2'-fluoro)arabinoriboside
Synonyms:2-AMino-6-chloropurine -9-beta-D-(2'-deoxy-3',5'-di-O-benzoyl-2'-fluoro)arabinoriboside;2-AMino-6-chloro-9-(2-deoxy-3,5-di-O-benzoyl-2-fluoro-β-D-arabinofuranosyl)-9H-purine;6-Chloro-9-(3,5-di-O-benzoyl-2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-9H-purin-2-amine;2-Amino-6-chloro-9-(2-deoxy-3,5-di-O-benzoyl-2-fluoro-b-D-arabinofuranosyl)purine;9H-Purin-2-amine, 6-chloro-9-(3,5-di-O-benzoyl-2-deoxy-2-fluoro-β-D-arabinofuranosyl)-;2-Amino-6-chloropurine-9-β-D-(2’-deoxy-3’,5’-di-O-benzoyl-2’-fluoro)arabinoriboside;2-Amino-6-chloropurine-9-beta-d-(2'-deoxy-3',5'-di-o-benzoyl-2'-fluoro)arabinoriboside
CAS:118373-61-8
MF:C24H19ClFN5O5
MW:511.89
EINECS:
Product Categories:
Mol File:118373-61-8.mol
2-AMino-6-chloropurine -9-beta-D-(2'-deoxy-3',5'-di-O-benzoyl-2'-fluoro)arabinoriboside Structure
2-AMino-6-chloropurine -9-beta-D-(2'-deoxy-3',5'-di-O-benzoyl-2'-fluoro)arabinoriboside Chemical Properties
Melting point 89-93 °C(Solvent: Ethanol)
Boiling point 735.1±70.0 °C(Predicted)
density 1.58±0.1 g/cm3(Predicted)
pka1.69±0.10(Predicted)
Safety Information
MSDS Information
2-AMino-6-chloropurine -9-beta-D-(2'-deoxy-3',5'-di-O-benzoyl-2'-fluoro)arabinoriboside Usage And Synthesis
Uses2-Amino-6-chloropurine -9-beta-D-(2’-deoxy-3’,5’-di-O-benzoyl-2’-fluoro)arabinoriboside is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
References[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
2-AMino-6-chloropurine -9-beta-D-(2'-deoxy-3',5'-di-O-benzoyl-2'-fluoro)arabinoriboside Preparation Products And Raw materials
Raw materials6-Chloroguanine-->2-Deoxy-2-fluoro-alpha-D-arabinofuranosyl bromide 3,5-dibenzoate
Tag:2-AMino-6-chloropurine -9-beta-D-(2'-deoxy-3',5'-di-O-benzoyl-2'-fluoro)arabinoriboside(118373-61-8) Related Product Information
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