| Company Name: |
BioBioPha Co., Ltd.
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| Tel: |
0871-65217109 13211707573; |
| Email: |
y.liu@mail.biobiopha.com |
| Products Intro: |
Product Name:Gancaonin I
CAS:126716-36-7
Purity:97.0% Package:5mg Remarks:BBP03469
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| | Gancaonin I Basic information |
| Product Name: | Gancaonin I | | Synonyms: | Gancaonin I;4-[4,6-Dimethoxy-5-(3-methyl-2-buten-1-yl)-2-benzofuranyl]-1,3-benzenediol;1,3-Benzenediol, 4-[4,6-dimethoxy-5-(3-methyl-2-buten-1-yl)-2-benzofuranyl]- | | CAS: | 126716-36-7 | | MF: | C21H22O5 | | MW: | 354.4 | | EINECS: | | | Product Categories: | | | Mol File: | 126716-36-7.mol |  |
| | Gancaonin I Chemical Properties |
| Boiling point | 534.2±45.0 °C(Predicted) | | density | 1.212±0.06 g/cm3(Predicted) | | pka | 8.75±0.35(Predicted) | | form | Solid | | color | White to off-white |
| | Gancaonin I Usage And Synthesis |
| Uses | Gancaonin I, an Isoflavone, exhibits moderate inhibition on human carboxylesterase 2 (hCES2A) with IC50 of 1.72 μM. Gancaonin I inhibits hCES2A-mediated fluorescein diacetate (FD) hydrolysis[1]. | | Definition | ChEBI: Gancaonin I is a member of the class of 1-benzofurans which consists of 1-benzofuran substituted by methoxy groups at positions 4 and 6, a prenyl group at position 5 and a 2,4-dihydroxyphenyl group at position 2. It has been isolated from Glycyrrhiza uralensis. It has a role as an antibacterial agent and a plant metabolite. It is a member of 1-benzofurans, an aromatic ether and a member of resorcinols. It derives from a hydride of a 1-benzofuran. | | References | [1] Yun-Qing Song, et al. Discovery of hCES2A inhibitors from Glycyrrhiza inflate via combination of docking-based virtual screening and fluorescence-based inhibition assays. Food Funct. 2021 Jan 7;12(1):162-176. DOI:10.1039/d0fo02140g |
| | Gancaonin I Preparation Products And Raw materials |
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