7-Triethylsilyl-13-oxobaccatin III

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7-Triethylsilyl-13-oxobaccatin III Basic information
Product Name:7-Triethylsilyl-13-oxobaccatin III
Synonyms:7-Triethylsilyl-13-oxobaccatin III;BTTALQYJOGXVHR-OZARNXOVSA-N;7,11-Methano-1H-cyclodeca[3,4]benz[1,2-b]oxete-5,9(3H,6H)-dione, 6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,4,4a,10,11,12,12a,12b-octahydro-11-hydroxy-4a,8,13,13-tetramethyl-4-[(triethylsilyl)oxy]-, (2aR,4S,4aS,6R,11S,12S,12aR,12bS)-;13-Oxo-7-O-(triethylsilyl)-baccatin III;(1S,2S,3R,4S,7R,9S,10S,12R)-4,12-bis(acetyloxy)-1-hydroxy-10,14,17,17-tetramethyl-11,15-dioxo-9-[(triethylsilyl)oxy]-6-oxatetracyclo[11.3.1.0(3,10).0(4,7)]heptadec-13-en-2-yl benzoate
CAS:150665-56-8
MF:C37H50O11Si
MW:698.87
EINECS:
Product Categories:
Mol File:150665-56-8.mol
7-Triethylsilyl-13-oxobaccatin III Structure
7-Triethylsilyl-13-oxobaccatin III Chemical Properties
Melting point 212 °C
Boiling point 721.7±60.0 °C(Predicted)
density 1.24±0.1 g/cm3(Predicted)
storage temp. -20°C Freezer
solubility Chloroform (Slightly), Methanol (Slightly)
form Solid
pka11.98±0.70(Predicted)
color White
Safety Information
MSDS Information
7-Triethylsilyl-13-oxobaccatin III Usage And Synthesis
Chemical PropertiesOff-white Foam
Uses7-Triethylsilyl-13-oxobaccatin III is used in the preparation of taxol analogs as antineoplastic agents and taxoids derivatives useful due to their ability to activate murine macrophages and inhibit the growth of macrophage-like cells.
UsesBaccatin III (B101000) derivative, used in the preparation of taxol analogs as antineoplastic agents and taxoids derivatives useful due to their ability to activate murine macrophages and inhibit the growth of macrophage-like cells.
7-Triethylsilyl-13-oxobaccatin III Preparation Products And Raw materials
Preparation Products14β-Hydroxy-7-O-(triethylsilyl)-13-oxo Baccatin III
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