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| | Prednisone-d7 Basic information |
| Product Name: | Prednisone-d7 | | Synonyms: | Prednisone-d7 | | CAS: | | | MF: | C21H19D7O5 | | MW: | 365.471272446 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File |  |
| | Prednisone-d7 Chemical Properties |
| solubility | DMSO: slightly soluble |
| | Prednisone-d7 Usage And Synthesis |
| Description | Prednisone-d7 is intended for use as an internal standard for the quantification of prednisone (Item No. 20677) by GC- or LC-MS. Prednisone is a synthetic glucocorticoid with anti-inflammatory and immunosuppressant activities.1 It inhibits paw swelling induced by sodium urate in mice by 86% when administered at a dose of 12 mg/kg.2 Prednisone reduces release of IL-6, monocyte chemoattractant protein-2 (MCP-2), MCP-3, RANTES, and TNF-α in stented arteries in a rabbit model of atherosclerosis.3 Formulations containing prednisone have been used in the treatment of non-Hodgkin lymphoma as part of CHOP chemotherapy and as anti-inflammatory or immunosuppressive agents.WARNING This product is not for human or veterinary use. | | References | [1] TELLER W. Metabolism of adrenal cortical steroids during the newborn period.[J]. Zeitschrift fur klinische Chemie und klinische Biochemie, 1969, 7 2: 210.
[2] T J FITZGERALD E M U B Williams. Effects of antimitotic and anti-inflammatory agents on sodium urate-induced paw swelling in mice.[J]. Pharmacology, 1971, 6 5: 265-273. DOI: 10.1159/000136252
[3] FLAVIO RIBICHINI MD . Effects of Oral Prednisone After Stenting in a Rabbit Model of Established Atherosclerosis[J]. Journal of the American College of Cardiology, 2007, 50 2: Pages 176-185. DOI: 10.1016/j.jacc.2007.03.031 |
| | Prednisone-d7 Preparation Products And Raw materials |
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