2'-Deoxy-2'-fluoro-alpha-D-arabinoguanosine

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2'-Deoxy-2'-fluoro-alpha-D-arabinoguanosine manufacturers
2'-Deoxy-2'-fluoro-alpha-D-arabinoguanosine Basic information
Product Name:2'-Deoxy-2'-fluoro-alpha-D-arabinoguanosine
Synonyms:2'-Deoxy-2'-fluoro-alpha-D-arabinoguanosine;9-(2'-Deoxy-2'-fluoro-a-D-arabinofuranosyl)guanine;2’-Deoxy-2’-fluoro-alpha-D-arabinoguanosine;2-phenoxy-1-[4-(piperidin-1-yl)-1-oxa-9-azaspiro[5.5]undecan-9-yl]ethan-1-one
CAS:2072145-29-8
MF:C10H12FN5O4
MW:285.24
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Mol File:2072145-29-8.mol
2'-Deoxy-2'-fluoro-alpha-D-arabinoguanosine Structure
2'-Deoxy-2'-fluoro-alpha-D-arabinoguanosine Chemical Properties
Boiling point 726.1±70.0 °C(Predicted)
density 2.17±0.1 g/cm3(Predicted)
pka12.68±0.70(Predicted)
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MSDS Information
2'-Deoxy-2'-fluoro-alpha-D-arabinoguanosine Usage And Synthesis
Uses2’-Deoxy-2’-fluoro-alpha-D-arabinoguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
References[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
2'-Deoxy-2'-fluoro-alpha-D-arabinoguanosine Preparation Products And Raw materials
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