| Company Name: |
BOC Sciences |
| Tel: |
+1-631-485-4226 |
| Email: |
inquiry@bocsci.com |
NK314 manufacturers
- NK314
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- $17900.00
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2026-08-26
- CAS:208237-49-4
- Purity:
- Supply Ability: 10g
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| Product Name: | NK314 | | Synonyms: | NK314;FXBDAIVJLCTTAW-UHFFFAOYSA-N;NK-314; NK 314 | | CAS: | 208237-49-4 | | MF: | C22H18ClNO4 | | MW: | 395.84 | | EINECS: | | | Product Categories: | | | Mol File: | 208237-49-4.mol |  |
| | NK314 Chemical Properties |
| | NK314 Usage And Synthesis |
| Uses | NK 314 is an inhibitor for topoisomerase IIα, which generates the break of DNA double-strand. NK 314 arrests the cell cycle at G2 phase in human acute myeloid leukemia cells, inhibits the proliferation of CEM with IC90 of 55 nM[1]. | | IC 50 | topoisomerase II alpha | | References | [1] Guo L, et al., Inhibition of topoisomerase IIalpha and G2 cell cycle arrest by NK314, a novel benzo[c]phenanthridine currently in clinical trials. Mol Cancer Ther. 2007 May;6(5):1501-8. DOI:10.1158/1535-7163.MCT-06-0780 |
| | NK314 Preparation Products And Raw materials |
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