PKH67 Green Fluorescent Cell Linker Midi Kit for General Cell Membrane Labeling

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PKH67 Green Fluorescent Cell Linker Midi Kit for General Cell Membrane Labeling Suppliers list
Company Name: Sigma-Aldrich  
Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
PKH67 Green Fluorescent Cell Linker Midi Kit for General Cell Membrane Labeling Basic information
Product Name:PKH67 Green Fluorescent Cell Linker Midi Kit for General Cell Membrane Labeling
Synonyms:PKH67 Green Fluorescent Cell Linker Midi Kit for General Cell Membrane Labeling
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PKH67 Green Fluorescent Cell Linker Midi Kit for General Cell Membrane Labeling Structure
PKH67 Green Fluorescent Cell Linker Midi Kit for General Cell Membrane Labeling Chemical Properties
Fp 14 °C
storage temp. room temp
Major Applicationcell analysis
detection
Safety Information
Hazard Codes F
Risk Statements 11
Safety Statements 7-16
RIDADR UN 3316 9
Storage Class3 - Flammable liquids
Hazard ClassificationsEye Irrit. 2
Flam. Liq. 2
MSDS Information
PKH67 Green Fluorescent Cell Linker Midi Kit for General Cell Membrane Labeling Usage And Synthesis
UsesPKH67 Green Fluorescent Cell Linker Midi Kit has been used for:
  • labeling exosomes
  • extracellular vesicles (EVs)l
  • normal and sickle red blood cells (RBCs)
  • Raji cells

General DescriptionThis kit is for general cell membrane labeling. PKH67 has a longer aliphatic carbon tail than PKH1 and PKH2, two other green dyes previously described for in vitro and in vivo cell tracking. Based on the longer tail length, in-house studies have consistently shown reduced cell-cell transfer for PKH67 as compared to PKH2.
Slow loss of fluorescence has been observed in in vivo studies using PKH1 and PKH2. PKH67 may exhibit similar properties since this behavior appears to be characteristic of green cell linker dyes, but not red cell linker dyes. Correlation of in vitro cell membrane retention with in vivo fluorescence half life in non-dividing cells predicts an in vivo fluorescence half life of 10-12 days for PKH67. Other green cell linker dyes with similar half lives have been used to monitor in vivo lymphocyte and macrophage trafficking over periods of 1-2 months, suggesting that PKH67 will also be useful for in vivo tracking studies of moderate length.
PKH67 Green Fluorescent Cell Linker Midi Kit for General Cell Membrane Labeling Preparation Products And Raw materials
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