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Product Name:Peucedanocoumarin III
CAS:130464-57-2
Purity:HPLC>=98% Package:5mg;10mg;20mg;50mg;100mg;200mg;500mg;1g
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Wuhan ChemFaces Biochemical Co., Ltd.
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Product Name:Peucedanocoumarin III
CAS:130464-57-2
Purity:>=98% Package:5mg ,10mg ,20mg ,50mg ,100mg; 200mg; 500mg,可根据客户需求定制
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EMMX Biotechnology LLC
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| Products Intro: |
Product Name:Peucedanocoumarin III
CAS:130464-57-2
Purity:98% HPLC Package:5mg;10mg;25mg;50mg;100mg;250mg;500mg;1g
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| | Peucedanocoumarin III Basic information |
| Product Name: | Peucedanocoumarin III | | Synonyms: | Peucedanocoumarin III;(2E)-2-Methyl-2-butenoic acid (9S,10R)-9-(acetyloxy)-9,10-dihydro-8,8-dimethyl-2-oxo-2H,8H-benzo[1,2-b:3,4-b']dipyran-10-yl ester;2-Butenoic acid, 2-methyl-, (9S,10R)-9-(acetyloxy)-9,10-dihydro-8,8-dimethyl-2-oxo-2H,8H-benzo[1,2-b:3,4-b']dipyran-10-yl ester, (2E)- | | CAS: | 130464-57-2 | | MF: | C21H22O7 | | MW: | 386.4 | | EINECS: | | | Product Categories: | | | Mol File: | 130464-57-2.mol |  |
| | Peucedanocoumarin III Chemical Properties |
| Boiling point | 486.8±45.0 °C(Predicted) | | density | 1.28±0.1 g/cm3(Predicted) | | solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | | form | Powder |
| | Peucedanocoumarin III Usage And Synthesis |
| Description | Peucedanocoumarin Ⅲ can induce rice resistance to blast disease. | | Uses | Peucedanocoumarin III is an inhibitor of (alpha)-synuclein and Huntington protein aggregates that enhances the clearance of nuclear and cytoplasmic β23 aggregates and prevents cytotoxicity induced by disease-associated proteins (i.e., mutant Huntington proteins and α-synuclein). Peucedanocoumarin III may be used in Parkinson's disease research[1]. | | IC 50 | α-synuclein Aggregation | | References | [1] Sangwoo Ham, et al. Cell-Based Screen Using Amyloid Mimic β23 Expression Identifies Peucedanocoumarin III as a Novel Inhibitor of α-Synuclein and Huntingtin Aggregates. Mol Cells. 2019 Jun 30;42(6):480-494. DOI:10.14348/molcells.2019.0091 |
| | Peucedanocoumarin III Preparation Products And Raw materials |
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