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| | Iseganan Basic information |
| Product Name: | Iseganan | | Synonyms: | Iseganan;L-Argininamide, L-arginylglycylglycyl-L-leucyl-L-cysteinyl-L-tyrosyl-L-cysteinyl-L-arginylglycyl-L-arginyl-L-phenylalanyl-L-cysteinyl-L-valyl-L-cysteinyl-L-valylglycyl-, cyclic (5→14),(7→12)-bis(disulfide) | | CAS: | 257277-05-7 | | MF: | C78H126N30O18S4 | | MW: | 1900.29 | | EINECS: | 000-000-0 | | Product Categories: | | | Mol File: | 257277-05-7.mol |  |
| | Iseganan Chemical Properties |
| form | Solid | | color | White to off-white |
| | Iseganan Usage And Synthesis |
| Uses | Iseganan is an antimi crobial peptide intended for use in the reduction in the severity of oral mucositis; oral decontamination in ventilator-associated pneumonia; aerosol formulation for control of infections in patients with cystic fibrosis. | | in vivo | Iseganan (intraperitoneal injection; 200 and 400 μg per mouse; once) shows anti-parasite activity in T. crassiceps murine cysticercosis model[3]. | Animal Model: | Female BALB/cAnN mice injected with T. crassiceps[3] | | Dosage: | 200 and 400 μg per mouse | | Administration: | Intraperitoneal injection; 200 and 400 μg per mouse; once | | Result: | Reduced the parasite load by 25% when compared with the control group. |
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| | Iseganan Preparation Products And Raw materials |
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