BETA-D-RIBOFURANURONAMIDE, 1-DEOXY-1-[6-[(2,2-DIPHENYLETHYL)AMINO]-2-[[[2-[[[[1-(2-PYRIDINYL)-4-PIPERIDINYL]AMINO]CARBONYL]AMINO]ETHYL]AMINO]CARBONYL]-9H-PURIN-9-YL]-N-ETHYL-
| 中文名称 | BETA-D-RIBOFURANURONAMIDE, 1-DEOXY-1-[6-[(2,2-DIPHENYLETHYL)AMINO]-2-[[[2-[[[[1-(2-PYRIDINYL)-4-PIPERIDINYL]AMINO]CARBONYL]AMINO]ETHYL]AMINO]CARBONYL]-9H-PURIN-9-YL]-N-ETHYL- |
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| 中文同义词 | 化合物 T29049;化合物 UK-432097 |
| 英文名称 | BETA-D-RIBOFURANURONAMIDE, 1-DEOXY-1-[6-[(2,2-DIPHENYLETHYL)AMINO]-2-[[[2-[[[[1-(2-PYRIDINYL)-4-PIPERIDINYL]AMINO]CARBONYL]AMINO]ETHYL]AMINO]CARBONYL]-9H-PURIN-9-YL]-N-ETHYL- |
| 英文同义词 | BETA-D-RIBOFURANURONAMIDE, 1-DEOXY-1-[6-[(2,2-DIPHENYLETHYL)AMINO]-2-[[[2-[[[[1-(2-PYRIDINYL)-4-PIPERIDINYL]AMINO]CARBONYL]AMINO]ETHYL]AMINO]CARBONYL]-9H-PURIN-9-YL]-N-ETHYL-;UK 432097;β-D-Ribofuranuronamide, 1-deoxy-1-[6-[(2,2-diphenylethyl)amino]-2-[[[2-[[[[1-(2-pyridinyl)-4-piperidinyl]amino]carbonyl]amino]ethyl]amino]carbonyl]-9H-purin-9-yl]-N-ethyl-;UK-432097 >=98% (HPLC) |
| CAS号 | 380221-63-6 |
| 分子式 | C40H47N11O6 |
| 分子量 | 777.89 |
| EINECS号 | |
| 相关类别 | |
| Mol文件 | 380221-63-6.mol |
| 结构式 | ![BETA-D-RIBOFURANURONAMIDE, 1-DEOXY-1-[6-[(2,2-DIPHENYLETHYL)AMINO]-2-[[[2-[[[[1-(2-PYRIDINYL)-4-PIPERIDINYL]AMINO]CARBONYL]AMINO]ETHYL]AMINO]CARBONYL]-9H-PURIN-9-YL]-N-ETHYL- 结构式](CAS/20180808/GIF/380221-63-6.gif) |
BETA-D-RIBOFURANURONAMIDE, 1-DEOXY-1-[6-[(2,2-DIPHENYLETHYL)AMINO]-2-[[[2-[[[[1-(2-PYRIDINYL)-4-PIPERIDINYL]AMINO]CARBONYL]AMINO]ETHYL]AMINO]CARBONYL]-9H-PURIN-9-YL]-N-ETHYL- 性质
| 密度 | 1.46±0.1 g/cm3(Predicted) |
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| 储存条件 | -20°C |
| 溶解度 | DMSO: 2mg/mL, clear |
| 形态 | 固体 |
| 酸度系数(pKa) | 9.85±0.46(Predicted) |
| 颜色 | 白色至米白色 |
| InChIKey | ZOTHAEBAWXWVID-HXEFRTELSA-N |
| SMILES | O[C@@H]1[C@@H](C(NCC)=O)O[C@@H](N2C=NC(C2=N3)=C(NCC(C4=CC=CC=C4)C5=CC=CC=C5)N=C3C(NCCNC(NC(CC6)CCN6C7=CC=CC=N7)=O)=O)[C@@H]1O |
BETA-D-RIBOFURANURONAMIDE, 1-DEOXY-1-[6-[(2,2-DIPHENYLETHYL)AMINO]-2-[[[2-[[[[1-(2-PYRIDINYL)-4-PIPERIDINYL]AMINO]CARBONYL]AMINO]ETHYL]AMINO]CARBONYL]-9H-PURIN-9-YL]-N-ETHYL- 用途与合成方法
UK-432097 是一种高效的选择性 A2AAR 激动剂，对人 A2AAR 的 pKi 为 8.4。UK-432097 具有抗炎和抗凝剂。UK-432097 具有用于 COPD (慢性阻塞性肺病)研究的潜力。
安全信息
| WGK Germany | WGK 3 |
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| 存储类别 | 11 - 可燃固体 |