9-[2,5-Anhydro-4-C-(hydroxymethyl)-alpha-L-lyxofuranosyl]-9H-purin-6-amine

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9-[2,5-Anhydro-4-C-(hydroxymethyl)-alpha-L-lyxofuranosyl]-9H-purin-6-amine Basic information
Product Name:9-[2,5-Anhydro-4-C-(hydroxymethyl)-alpha-L-lyxofuranosyl]-9H-purin-6-amine
Synonyms:9-[2,5-Anhydro-4-C-(hydroxymethyl)-alpha-L-lyxofuranosyl]-9H-purin-6-amine;2'-O,4'-C-Methyleneadenosine;9H-Purin-6-amine, 9-[2,5-anhydro-4-C-(hydroxymethyl)-α-L-lyxofuranosyl]-;2’-O,4’-C-Methyleneadenosine, LNA-A;4'-C-Methyleneadenosine;LNA Adenosine;9-[2,5-Anhydro-4-C-(hydroxymethyl)-α-L-lyxofuranosyl]-9H-purin-6-amine;2'-O-4'-C-locked-Adenosine
CAS:206055-70-1
MF:C11H13N5O4
MW:279.25
EINECS:
Product Categories:Nucleosides;Nucleosides-LNA Nucleosides
Mol File:206055-70-1.mol
9-[2,5-Anhydro-4-C-(hydroxymethyl)-alpha-L-lyxofuranosyl]-9H-purin-6-amine Structure
9-[2,5-Anhydro-4-C-(hydroxymethyl)-alpha-L-lyxofuranosyl]-9H-purin-6-amine Chemical Properties
Boiling point 660.0±65.0 °C(Predicted)
density 2.14±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
pka12.98±0.60(Predicted)
form Solid
color White to off-white
InChIInChI=1/C11H13N5O4/c12-8-5-9(14-3-13-8)16(4-15-5)10-6-7(18)11(1-17,20-10)2-19-6/h3-4,6-7,10,17-18H,1-2H2,(H2,12,13,14)/t6-,7+,10-,11+/s3
InChIKeyGHKDRNDFVCEETA-MIRGOXCMNA-N
SMILES[C@@]12([H])[C@]([H])(O)[C@@](CO)(O[C@H]1N1C3=C(N=C1)C(N)=NC=N3)CO2 |&1:0,2,5,9,r|
Safety Information
MSDS Information
9-[2,5-Anhydro-4-C-(hydroxymethyl)-alpha-L-lyxofuranosyl]-9H-purin-6-amine Usage And Synthesis
Uses2'-O,4'-C-Methyleneadenosine (LNA-A) is a locked nucleic acid (LNA) and is also an adenosine analog[1].
Biological Activity2'-O,4'-C-Methyleneadenosine (LNA-A) is a locked nucleic acid (LNA) and is also an adenosine analog[1].
References[1]. Ravn J, et al. Design, synthesis, and biological evaluation of LNA nucleosides as adenosine A3 receptor ligands. Bioorg Med Chem. 2007 Aug 15;15(16):5440-7.
9-[2,5-Anhydro-4-C-(hydroxymethyl)-alpha-L-lyxofuranosyl]-9H-purin-6-amine Preparation Products And Raw materials
Preparation ProductsBenzamide, N-[9-[2,5-anhydro-4-C-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-α-L-lyxofuranosyl]-9H-purin-6-yl]-
Tag:9-[2,5-Anhydro-4-C-(hydroxymethyl)-alpha-L-lyxofuranosyl]-9H-purin-6-amine(206055-70-1) Related Product Information
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