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ST 198 manufacturers
- ST-198
-
- $1980.00
-
2026-05-11
- CAS:854924-64-4
- Purity:
- Supply Ability: 10g
|
| Product Name: | ST 198 | | Synonyms: | 2-Propenamide, N-[4-(3,4-dihydro-2(1H)-isoquinolinyl)butyl]-3-phenyl-, (2E)- | | CAS: | 854924-64-4 | | MF: | C22H26N2O | | MW: | 334.45 | | EINECS: | | | Product Categories: | | | Mol File: | 854924-64-4.mol |  |
| | ST 198 Chemical Properties |
| Boiling point | 556.2±50.0 °C(Predicted) | | density | 1.093±0.06 g/cm3(Predicted) | | pka | 15.30±0.46(Predicted) |
| | ST 198 Usage And Synthesis |
| Description | ST-198 is anantagonist of dopamine D3 receptor. | | Uses | ST 198 is an orally active D3R antagonist. ST 198 can block the expression of nicotine-induced CPP at doses selective for D3R. ST 198 can be used for the research of neurological disease[1]. | | in vivo | ST 198 (p.o.; 3, 30, 100 mg/kg) inhibits the expression of nicotine CPPs[1]. | Animal Model: | Rats[1]. | | Dosage: | 3, 30, 100 mg/kg | | Administration: | p.o | | Result: | Displayed nicotine-induced CPP. |
| | References | [1] Le Foll B, et al. Dopamine D3 receptor ligands block nicotine-induced conditioned place preferences through a mechanism that does not involve discriminative-stimulus or antidepressant-like effects. Neuropsychopharmacology. 2005;30(4):720-730. DOI:10.1038/sj.npp.1300622 |
| | ST 198 Preparation Products And Raw materials |
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