(S)-ethyl 2-(((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate

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(S)-ethyl 2-(((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate Suppliers list
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(S)-ethyl 2-(((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate Basic information
Product Name:(S)-ethyl 2-(((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate
Synonyms:(S)-ethyl 2-(((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate;(S)-2-{[(2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-ylmethoxy](phenoxy)phosphorylamino}propionicacidethylester;Sofosbuvir ethyl ester impuriy;sofosbuvir Ethyl ester imp;Ethyl sofosbuvirQ: What is Ethyl sofosbuvir Q: What is the CAS Number of Ethyl sofosbuvir Q: What is the storage condition of Ethyl sofosbuvir Q: What are the applications of Ethyl sofosbuvir;L-Alanine, N-[(2'R)-2'-deoxy-2'-fluoro-2'-methyl-P-phenyl-5'-uridylyl]-, ethyl ester;Modafinil Impurity 13;Sofosbuvir ethyl analog (mixture of isomers)
CAS:1064684-30-5
MF:C21H27FN3O9P
MW:515.43
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Mol File:1064684-30-5.mol
(S)-ethyl 2-(((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate Structure
(S)-ethyl 2-(((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate Chemical Properties
density 1.44±0.1 g/cm3(Predicted)
pka9.39±0.10(Predicted)
Safety Information
MSDS Information
(S)-ethyl 2-(((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate Usage And Synthesis
UsesSofosbuvir O-Desisopropyl O-Ethyl Ester is a useful reagent for synthesizingβ-D-2''-Deoxy-2''-α-fluoro-2''-β-C-methyluridine nucleotide that can selectively inhibit Hepatitis C virus (HCV) NS5B polymerase, which is a potential target for developing therapies for HCV.Sofosbuvir O-Desisopropyl O-Ethyl Ester is also an impurity of Sofosbuvir (P839640).
(S)-ethyl 2-(((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate Preparation Products And Raw materials
Tag:(S)-ethyl 2-(((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate(1064684-30-5) Related Product Information
Sofosbuvir metabolites Sofosbuvir IMpurity C (2R)-2-Deoxy-2-fluoro-2-Methyl-D-erythro-pentonic acid-g-lactone 3,5-bis(4-chlorobenzoate) ((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methyl benzoate Phenol, 2,3,4,5-tetrafluoro- Phenol, 2,3,4,6-tetrafluoro- SofosBuvir Impurity 53 L-Alanine, N-[(S)-hydroxyphenoxyphosphinyl]-, 1-Methylethyl ester, (P→3'),(P'→5')-diester with (2'R)-2'-deoxy-2'-fluoro-2'-Methyluridine diisopropylphenylphosphate Sofosbuvir Impurity 104 PSI 7411 Sofosbuvir IMpurity Sofosbuvir Impurity 108 D-Ribonic acid, 2-C-methyl-, γ-lactone, 3,5-dibenzoate Sofosbuvir IMpurity B ((2R,3S,4S)-3-(benzoyloxy)-4-fluoro-4-Methyl-5-oxotetrahydrofuran-2-yl)Methyl benzoate PSI-7976 Tris(phenyl,methylphenyl,ethylphenylandnonylphenyl)phosphate