Methyl 8-(tert-butyl)-6-chloroimidazo[1,2-b]pyridazine-2-carboxylate

Request For Quotation
Methyl 8-(tert-butyl)-6-chloroimidazo[1,2-b]pyridazine-2-carboxylate Suppliers list
Company Name: BOC Sciences  
Tel: 1-631-485-4226; 16314854226
Email: info@bocsci.com
Company Name: ShangHai Caerulum Pharma Discovery Co., Ltd.  
Tel: 18149758185 18149758185
Email: sales-cpd@caerulumpharma.com
Company Name: Shanghai Lollane Biological Technology Co.,Ltd.  
Tel: 021-52996696，15000506266 15000506266
Email:
Company Name: Shanghai YuanYe Biotechnology Co., Ltd.  
Tel: 15026964105
Email: 2881489226@qq.com
Company Name: ShangHai Biochempartner Co.,Ltd  
Tel: 177-54423994 17754423994
Email: 2853530910@QQ.com

Methyl 8-(tert-butyl)-6-chloroimidazo[1,2-b]pyridazine-2-carboxylate manufacturers

  • PAR-2-IN-1
  • PAR-2-IN-1 pictures
  • $30.00
  • 2026-07-27
  • CAS:1690176-75-0
  • Purity: 99.79%
  • Supply Ability: 10g
Methyl 8-(tert-butyl)-6-chloroimidazo[1,2-b]pyridazine-2-carboxylate Basic information
Product Name:Methyl 8-(tert-butyl)-6-chloroimidazo[1,2-b]pyridazine-2-carboxylate
Synonyms:Methyl 8-(tert-butyl)-6-chloroimidazo[1,2-b]pyridazine-2-carboxylate;Imidazo[1,2-b]pyridazine-2-carboxylic acid, 6-chloro-8-(1,1-dimethylethyl)-, methyl ester;IUN76750;PAR-2-IN-1;PAR-2 inhibitor;Methyl 8-(tert-butyl)-6-chloroimidazo[1,2-b]pyridazine-2-car;Inhibitor,PAR2IN1,anti-inflammatory,anticancer,PAR 2 IN 1,inhibit,PAR2,Thrombin receptors,Protease Activated Receptor (PAR);PAR-2-IN-1, 10 mM in DMSO
CAS:1690176-75-0
MF:C12H14ClN3O2
MW:267.71
EINECS:
Product Categories:
Mol File:1690176-75-0.mol
Methyl 8-(tert-butyl)-6-chloroimidazo[1,2-b]pyridazine-2-carboxylate Structure
Methyl 8-(tert-butyl)-6-chloroimidazo[1,2-b]pyridazine-2-carboxylate Chemical Properties
density 1.31±0.1 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
solubility DMSO : 83.33 mg/mL (311.27 mM; Need ultrasonic)
pka0.85±0.30(Predicted)
form Solid
color White to light yellow
Safety Information
MSDS Information
Methyl 8-(tert-butyl)-6-chloroimidazo[1,2-b]pyridazine-2-carboxylate Usage And Synthesis
UsesPAR-2-IN-1 is a protease-activated receptor-2 (PAR2) signaling pathway inhibitor with anti-inflammatory and anticancer effects[1].
IC 50PAR2
References[1] Luc J. Farmer, et al. Imidazopyridazines useful as inhibitors of the par-2 signaling pathway. WO2015048245A1.
Methyl 8-(tert-butyl)-6-chloroimidazo[1,2-b]pyridazine-2-carboxylate Preparation Products And Raw materials
Tag:Methyl 8-(tert-butyl)-6-chloroimidazo[1,2-b]pyridazine-2-carboxylate(1690176-75-0) Related Product Information
6-Chloro-imidazo[1,2-b]pyridazine-2-carboxylic acid, methyl ester Ethyl 6-chloroimidazo[1,2-b]pyridazine-2-carboxylate 6-Chloroimidazo[1,2-b]pyridazine-2-carboxylic acid Imidazo[1,2-b]pyridazine-2-carboxylic acid, 6-chloro-8-(1-methylethyl)-, methyl ester Imidazo[1,2-b]pyridazine-3-carboxylic acid, 6-chloro-8-methyl-, ethyl ester Imidazo[1,2-b]pyridazine-3-carboxylic acid, 6-chloro-8-methyl-