| Company Name: |
Quality Control Solutions Ltd.
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| Tel: |
0755-66853366 13670046396 |
| Email: |
orders@qcsrm.com |
| Products Intro: |
Product Name:1-Amino Adamantane-d6
CAS:1219805-53-4
Purity:95% HPLC Package:10mg;25mg;50mg;100mg
|
| Company Name: |
Alta Scientific Co., Ltd.
|
| Tel: |
022-6537-8550 15522853686 |
| Email: |
sales@altasci.com.cn |
| Products Intro: |
Product Name:Adamantanamine-d6
CAS:1219805-53-4
Purity:99% Package:10mg;100mg;1g
|
| Company Name: |
Shenzhen SUNGENING Bio-Medical Co., Ltd.
|
| Tel: |
0755-28967200 13631290199 |
| Email: |
wxf@sungening.com |
| Products Intro: |
Product Name:Amantadine D6
CAS:1219805-53-4
Purity:99% HPLC or More Package:10MG;25MG;50MG;100MG
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- Amantadine-D6
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2026-05-11
- CAS:1219805-53-4
- Purity:
- Supply Ability: 10g
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| | 1-Aminoadamantane-2,2,2′,2′,2″,2″-d6 Basic information |
| Product Name: | 1-Aminoadamantane-2,2,2′,2′,2″,2″-d6 | | Synonyms: | 1-Aminoadamantane-2,2,2′,2′,2″,2″-d6;[2H6]-Amantadine;Amantadine-d6 (1-Amino Adamantane-d6);1-Aminoadamantane-2,2,2',2',2'',2''-d6 Solution in Methanol, 100μg/mL;Adamantanamine-d6 Solution, 100μg/mL;Amantadine-d6
DISCONTINUED, offer A575822 / A575823;Adamantanamine-d6;Amantadine D6Q: What is
Amantadine D6 Q: What is the CAS Number of
Amantadine D6 Q: What is the storage condition of
Amantadine D6 Q: What are the applications of
Amantadine D6 | | CAS: | 1219805-53-4 | | MF: | C10H17N | | MW: | 151.25 | | EINECS: | | | Product Categories: | | | Mol File: | 1219805-53-4.mol |  |
| | 1-Aminoadamantane-2,2,2′,2′,2″,2″-d6 Chemical Properties |
| form | Solid | | color | White to off-white |
| | 1-Aminoadamantane-2,2,2′,2′,2″,2″-d6 Usage And Synthesis |
| Uses | Amantadine-d6 is the deuterium labeled Amantadine[1]. Amantadine (1-Adamantanamine) is an orally avtive and potent antiviral agent with activity against influenza A viruses. Amantadine inhibits several ion channels such as NMDA and M2, and also inhibits Coronavirus ion channels. Amantadine also has anti-orthopoxvirus and anticancer activity. Amantadine can be used for Parkinson's disease, postoperative cognitive dysfunction (POCD) and COVID-19 research[2][3][4][5][6][7]. | | References | [1] Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. DOI:10.1177/1060028018797110
[2] Suzuki H, et al. Emergence of amantadine-resistant influenza A viruses: epidemiological study. J Infect Chemother. 2003;9(3):195-200. DOI:10.1007/s10156-003-0262-6
[3] Hubsher G, et al. Amantadine: the journey from fighting flu to treating Parkinson disease. Neurology. 201278(14):1096-1099. DOI:10.1212/WNL.0b013e31824e8f0d
[4] Donald F Smee, et al. A review of compounds exhibiting anti-orthopoxvirus activity in animal models. Antiviral Res. 2003 Jan57(1-2):41-52. DOI:10.1016/s0166-3542(02)00199-7
[5] Fink K, et al. Amantadine Inhibits SARS-CoV-2 In Vitro. Viruses. 2021 Mar 2413(4):539. DOI:10.3390/v13040539
[6] Zhang J, et al. Amantadine alleviates postoperative cognitive dysfunction possibly by increasing glial cell line-derived neurotrophic factor in rats. Anesthesiology. 2014 Oct121(4):773-85. DOI:10.1097/ALN.0000000000000352
[7] Lan Z, et al. Amantadine inhibits cellular proliferation and induces the apoptosis of hepatocellular cancer cells in vitro. Int J Mol Med. 201536(3):904-910. DOI:10.3892/ijmm.2015.2289 |
| | 1-Aminoadamantane-2,2,2′,2′,2″,2″-d6 Preparation Products And Raw materials |
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