tert-Butyl (6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexyl)carbamate

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tert-Butyl (6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexyl)carbamate Basic information
Product Name:tert-Butyl (6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexyl)carbamate
Synonyms:N-[N'-(tert-butyloxycarbonyl)-6-aminohexyl]maleimide;tert-Butyl (6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexyl)carbamate;1-(6-N-Boc-aminohexyl)-1H-pyrrole-2,5-dione;tert-Butyl N-[6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexyl]carbamate;Carbamic acid, [6-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)hexyl]-, 1,1-dimethylethyl ester (9CI);Mal-C6-NH-Boc;Mal-C4-NH-Boc
CAS:124529-64-2
MF:C15H24N2O4
MW:296.36
EINECS:
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Mol File:124529-64-2.mol
tert-Butyl (6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexyl)carbamate Structure
tert-Butyl (6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexyl)carbamate Chemical Properties
Boiling point 445.8±28.0 °C(Predicted)
density 1.120±0.06 g/cm3(Predicted)
storage temp. 2-8°C
pka12.92±0.46(Predicted)
Safety Information
MSDS Information
tert-Butyl (6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexyl)carbamate Usage And Synthesis
UsesMal-C4-NH-Boc is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50Alkyl/ether
References[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
tert-Butyl (6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexyl)carbamate Preparation Products And Raw materials
Tag:tert-Butyl (6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexyl)carbamate(124529-64-2) Related Product Information
N-(6-Aminohexyl)maleimide hydrochloride salt N-Boc-2-maleimidoethylamine 1-(6-aminohexyl)-1H-Pyrrole-2,5-dione CarbaMic acid, [5-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)pentyl]-, 1,1-diMethylethyl ester CarbaMic acid, [4-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)butyl]-, 1,1-diMethylethyl ester [3-(2,5-dioxo-2,5-dihydro-pyrrol-1-y1)-propyl]-carbaMic acid tert-butyl ester