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Super-TDU

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Company Name: Shenzhen Nexconn Pharmatechs Ltd
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Products Intro: Product Name:Super-TDU
CAS:1599441-71-0
Purity:98% Package:1KG;10KG;50KG
Company Name: TargetMol Chemicals Inc.
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Products Intro: Product Name:Super-TDU
CAS:1599441-71-0
Package:1 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: Career Henan Chemica Co
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Products Intro: Product Name:Super-TDU
CAS:1599441-71-0
Purity:99% Package:1KG;7USD
Company Name: InvivoChem
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Products Intro: Product Name:Super-TDU
CAS:1599441-71-0
Purity:98% Package:5mg Remarks:V3198
Company Name: Aladdin Scientific
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Products Intro: Product Name:Super-TDU TFA
CAS:1599441-71-0
Purity:98% Package:$101.9/1mg;$356.9/5mg;$570.9/10mg;Bulk package Remarks:98%
Super-TDU Basic information
Product Name:Super-TDU
Synonyms:Super-TDU;Super-TDU TFA
CAS:1599441-71-0
MF:C237H370N66O69S
MW:5279.9395
EINECS:
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Mol File:1599441-71-0.mol
Super-TDU Structure
Super-TDU Chemical Properties
storage temp. Store at -20°C
form Solid
color White to off-white
SequenceSer-Val-Asp-Asp-His-Phe-Ala-Lys-Ser-Leu-Gly-Asp-Thr-Trp-Leu-Gln-Ile-Gly-Gly-Ser-Gly-Asn-Pro-Lys-Thr-Ala-Asn-Val-Pro-Gln-Thr-Val-Pro-Met-Arg-Leu-Arg-Lys-Leu-Pro-Asp-Ser-Phe-Phe-Lys-Pro-Pro-Glu
Safety Information
MSDS Information
Super-TDU Usage And Synthesis
UsesSuper-TDU is a specific YAP antagonist targeting YAP-TEADs interaction. Super-TDU suppresses tumor growth in gastric cancer mouse model[1].
Biological ActivitySuper-TDU is an inhibitory polypeptide targeting YAP-TEADs interaction.
in vivoSuper-TDU can treat gastric cancer by directly targeting YAP-TEADs, unlike the traditional drug compound 5-FU, whose antitumor activity tends to be more towards tumors with a high ratio of YAP/VGLL4.
target
TargetValue
YAP/TEAD interaction
()
IC 50YAP/TAZ-TEAD
References[1] Jiao S, et al. A peptide mimicking VGLL4 function acts as a YAP antagonist therapy against gastric cancer. Cancer Cell. 2014 Feb 10;25(2):166-80. DOI:10.1016/j.ccr.2014.01.010
Super-TDU Preparation Products And Raw materials
Tag:Super-TDU(1599441-71-0) Related Product Information
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