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| | Bometolol Hydrochloride Basic information |
| | Bometolol Hydrochloride Chemical Properties |
| storage temp. | Store at -20°C | | solubility | Soluble in DMSO |
| | Bometolol Hydrochloride Usage And Synthesis |
| Uses | Bometolol Hydrochloride is a beta-adrenergic blocking agent, used for the research of cardiovascular disease. | | in vivo | Bometolol (10-30 mg/kg, p.o.) lowers the blood pressure dose-dependently in spontaneously hypertensive rats, deoxycorticosterone and salt hypertensive rats and two kindey, one clip hypertensive rats. In subchronic study, Bometolol (10-30 mg/kg, or 100-300 mg/kg, p.o.) dose-dependently decreases heart rate, plasma renin activity, heart and kindey weitht and incidence of vascular lesion, but shows no antihypertensive effects in all the hypertensive rats[1]. | | References | [1] Watanabe TX, et al. Acute and subchronic effects of bometolol on blood pressure in hypertensive rats. J Pharmacobiodyn. 1981 Jul;4(7):505-12. DOI:10.1248/bpb1978.4.505 |
| | Bometolol Hydrochloride Preparation Products And Raw materials |
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