bis-PEG2-endo-BCN manufacturers
- Bis-PEG2-endo-BCN
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2025-06-07
- CAS:1476737-97-9
- Min. Order: 25mg
- Purity: >95.00%
- Supply Ability: 100mg
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| | bis-PEG2-endo-BCN Basic information |
| Product Name: | bis-PEG2-endo-BCN | | Synonyms: | bis-PEG2-endo-BCN;5,8-Dioxa-2,11-diazadodecanedioic acid, 1,12-bis[(1R,8S)-bicyclo[6.1.0]non-4-yn-9-ylmethyl] ester, rel-;endo-BCN-PEG2-endo-BCN | | CAS: | 1476737-97-9 | | MF: | C28H40N2O6 | | MW: | 500.63 | | EINECS: | | | Product Categories: | | | Mol File: | 1476737-97-9.mol |  |
| | bis-PEG2-endo-BCN Chemical Properties |
| Boiling point | 668.3±45.0 °C(Predicted) | | density | 1.20±0.1 g/cm3(Predicted) | | solubility | Soluble in DMSO, DCM, DMF | | pka | 11.75±0.46(Predicted) | | form | Oil | | color | Colorless to light yellow |
| | bis-PEG2-endo-BCN Usage And Synthesis |
| Description | bis-PEG2-endo-BCN is a click chemistry reagent, The BCN group enable copper free click chemitry with azide-tagged molecules. | | Uses | bis-PEG2-endo-BCN is a cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. bis-PEG2-endo-BCN is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. | | IC 50 | Cleavable Linker | | References | [1] Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337. DOI:10.1038/nrd.2016.268 |
| | bis-PEG2-endo-BCN Preparation Products And Raw materials |
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