Bis-aminooxy-PEG2 manufacturers
|
| | Bis-aminooxy-PEG2 Basic information |
| Product Name: | Bis-aminooxy-PEG2 | | Synonyms: | Bis-aminooxy-PEG2;1,8-diaminooxy-3,6-dioxaoctane;Hydroxylamine, O,O'-[1,2-ethanediylbis(oxy-2,1-ethanediyl)]bis-;O,O'-((ethane-1,2-diylbis(oxy))bis(ethane-2,1-diyl))bis(hydroxylamine);O-(2-{2-[2-(aminooxy)ethoxy]ethoxy}ethyl)hydroxylamine;Bis-aminooxy-PEG2 dihydrochloride;O,O′-[1,2-Ethanediylbis(oxy-2,1-ethanediyl)]bis[hydroxylamine | | CAS: | 98627-71-5 | | MF: | C6H16N2O4 | | MW: | 180.2 | | EINECS: | | | Product Categories: | | | Mol File: | 98627-71-5.mol |  |
| | Bis-aminooxy-PEG2 Chemical Properties |
| Boiling point | 339.7±32.0 °C(Predicted) | | density | 1.123±0.06 g/cm3(Predicted) | | storage temp. | 2-8°C, protect from light | | solubility | Soluble in Water, DMSO, DMF | | pka | 4.51±0.70(Predicted) | | form | Liquid | | color | Colorless to light yellow |
| | Bis-aminooxy-PEG2 Usage And Synthesis |
| Description | Bis-aminooxy-PEG2 is a homobifunctional PEG linker with two aminooxy groups. The aminooxy group is reactive with aldehyde to form an oxime bond. If a reductant is applied, it will form a hydroxylamine linkage. Aminooxy compounds are very reactive and sensitive; they cannot be stored for long term. Immediate use (within 1 week) is highly recommended. | | Uses | Bis-aminooxy-PEG2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | | IC 50 | PEGs | | References | [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
| | Bis-aminooxy-PEG2 Preparation Products And Raw materials |
|