DSPE-PEG4-DBCO manufacturers
- DSPE-PEG4-DBCO
-
- $34.00 / 1mg
-
2026-01-27
- CAS:2112738-14-2
- Min. Order:
- Purity: ≥98%
- Supply Ability: 10g
- DSPE-PEG4-DBCO
-
- $0.00 / 100mg
-
2025-06-07
- CAS:2112738-14-2
- Min. Order: 100mg
- Purity: >98.00%
- Supply Ability: 100mg
|
| | DSPE-PEG4-DBCO Basic information |
| Product Name: | DSPE-PEG4-DBCO | | Synonyms: | DSPE-PEG4-DBCO;Octadecanoic acid, 1,1'-[(1R)-1-[27-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-3-hydroxy-3-oxido-8,23,27-trioxo-2,4,11,14,17,20-hexaoxa-7,24-diaza-3-phosphaheptacos-1-yl]-1,2-ethanediyl] ester | | CAS: | 2112738-14-2 | | MF: | C71H116N3O15P | | MW: | 1282.67 | | EINECS: | | | Product Categories: | | | Mol File: | 2112738-14-2.mol |  |
| | DSPE-PEG4-DBCO Chemical Properties |
| solubility | Soluble in DMSO, DCM, DMF |
| | DSPE-PEG4-DBCO Usage And Synthesis |
| Description | DSPE-PEG4-DBCO is a PEG linker containing DSPE and DBCO moieties. The DSPE-PEGs have been FDA approved for medical applications. The hydrophobic properties of the DSPE allow for the encapsulation and congregation of other hydrophobic drugs. The hydrophilic PEG linker increases the water solubility of the overall compound allowing for the delivery of the drug. The DBCO group can be used for copper-free Click Chemistry reactions. | | Uses | DSPE-PEG4-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. DSPE-PEG4-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. | | IC 50 | PEGs | | References | [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
| | DSPE-PEG4-DBCO Preparation Products And Raw materials |
|