- 4-Methoxy-3-pyridinamine
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- $200.00 / 1KG
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2025-09-25
- CAS:33631-09-3
- Min. Order: 1KG
- Purity: 99%, 99.5% Sublimated
- Supply Ability: g-kg-tons, free sample is available
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| | 3-AMINO-4-METHOXYPYRIDINE Basic information |
| | 3-AMINO-4-METHOXYPYRIDINE Chemical Properties |
| Melting point | 83 °C | | Boiling point | 270.4±20.0 °C(Predicted) | | density | 1.139±0.06 g/cm3(Predicted) | | storage temp. | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C | | form | solid | | pka | 7.48±0.18(Predicted) | | color | Brown | | InChI | InChI=1S/C6H8N2O/c1-9-6-2-3-8-4-5(6)7/h2-4H,7H2,1H3 | | InChIKey | STWMPIWLSQKHSJ-UHFFFAOYSA-N | | SMILES | C1=NC=CC(OC)=C1N |
| | 3-AMINO-4-METHOXYPYRIDINE Usage And Synthesis |
| Chemical Properties | Off-white solid | | Synthesis | Example 93: Synthesis of 4-hydroxy-4-[3-(trifluoromethyl)phenyl]piperidine-1-carboxylic acid (7-methoxy-thiazolo[5,4-b]pyridin-2-yl)-amide; Step 1: To a solution of 4-methoxy-3-nitropyridine (5.0 g, 32.44 mmol) in ethanol (100 mL) was added 10% palladium/carbon catalyst (200 mg). The reaction mixture was placed under hydrogen atmosphere (50 psi) and the reaction was shaken at room temperature for 6 hours. The progress of the reaction was monitored by thin layer chromatography (TLC, 50% ethyl acetate/hexane) to confirm complete conversion of the feedstock. Upon completion of the reaction, the catalyst was removed by diatomaceous earth filtration and the filtrate was concentrated under reduced pressure to afford 3-amino-4-methoxypyridine (4.0 g, 32.44 mmol, 100% yield), the product was a dark red oil. | | References | [1] Patent: US2007/270433, 2007, A1. Location in patent: Page/Page column 47
[2] Patent: WO2012/67664, 2012, A1. Location in patent: Page/Page column 53
[3] Inorganic Chemistry, 2013, vol. 52, # 7, p. 3653 - 3662
[4] Patent: US2011/9405, 2011, A1. Location in patent: Page/Page column 49-50
[5] Chemistry - A European Journal, 2012, vol. 18, # 51, p. 16358 - 16368 |
| | 3-AMINO-4-METHOXYPYRIDINE Preparation Products And Raw materials |
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