6-amino-8-[3-bromo-5-methoxy-4-(prop-2-en-1-yloxy)phenyl]-8H-[1,3]dioxolo[4,5-g]chromene-7-carbonitrile

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6-amino-8-[3-bromo-5-methoxy-4-(prop-2-en-1-yloxy)phenyl]-8H-[1,3]dioxolo[4,5-g]chromene-7-carbonitrile Suppliers list
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6-amino-8-[3-bromo-5-methoxy-4-(prop-2-en-1-yloxy)phenyl]-8H-[1,3]dioxolo[4,5-g]chromene-7-carbonitrile manufacturers
6-amino-8-[3-bromo-5-methoxy-4-(prop-2-en-1-yloxy)phenyl]-8H-[1,3]dioxolo[4,5-g]chromene-7-carbonitrile Basic information
Product Name:6-amino-8-[3-bromo-5-methoxy-4-(prop-2-en-1-yloxy)phenyl]-8H-[1,3]dioxolo[4,5-g]chromene-7-carbonitrile
Synonyms:6-amino-8-[3-bromo-5-methoxy-4-(prop-2-en-1-yloxy)phenyl]-8H-[1,3]dioxolo[4,5-g]chromene-7-carbonitrile;WAY-324166;8H-1,3-Dioxolo[4,5-g][1]benzopyran-7-carbonitrile, 6-amino-8-[3-bromo-5-methoxy-4-(2-propen-1-yloxy)phenyl]-;8-(4-(Allyloxy)-3-bromo-5-methoxyphenyl)-6-amino-8H-[1,3]dioxolo[4,5-g]chromene-7-carbonitrile;8H-1,3-Dioxolo[4,5-g][1]benzopyran-7-carbonitrile, 6-amino-8-[3-bromo-5-methoxy-4-(2-propen-1-yloxy)phenyl]- (ACI);Wnt pathway inhibitor 3
CAS:663213-98-7
MF:C21H17BrN2O5
MW:457.27
EINECS:
Product Categories:
Mol File:663213-98-7.mol
6-amino-8-[3-bromo-5-methoxy-4-(prop-2-en-1-yloxy)phenyl]-8H-[1,3]dioxolo[4,5-g]chromene-7-carbonitrile Structure
6-amino-8-[3-bromo-5-methoxy-4-(prop-2-en-1-yloxy)phenyl]-8H-[1,3]dioxolo[4,5-g]chromene-7-carbonitrile Chemical Properties
Boiling point 587.0±50.0 °C(Predicted)
density 1.59±0.1 g/cm3(Predicted)
pka2.69±0.40(Predicted)
form Solid
color White to off-white
Safety Information
MSDS Information
6-amino-8-[3-bromo-5-methoxy-4-(prop-2-en-1-yloxy)phenyl]-8H-[1,3]dioxolo[4,5-g]chromene-7-carbonitrile Usage And Synthesis
UsesWnt pathway inhibitor 3 is a potent wnt inhibitor with an IC50 value of 45 nM. Wnt pathway inhibitor 3 shows antiproliferative activity[1].
References[1] Michael Boutros, et al. Chromene derivatives and their analoga as wnt pathway antagonists. US20130296344A1.
6-amino-8-[3-bromo-5-methoxy-4-(prop-2-en-1-yloxy)phenyl]-8H-[1,3]dioxolo[4,5-g]chromene-7-carbonitrile Preparation Products And Raw materials
Tag:6-amino-8-[3-bromo-5-methoxy-4-(prop-2-en-1-yloxy)phenyl]-8H-[1,3]dioxolo[4,5-g]chromene-7-carbonitrile(663213-98-7) Related Product Information
8H-1,3-Dioxolo[4,5-g][1]benzopyran-7-carbonitrile, 6-amino-8-(3-bromo-4,5-dimethoxyphenyl)- Wortmannin-Rapamycin Conjugate Wnt/β-catenin agonist 1 3-Isoxazolecarboxamide, 5-(2-furanyl)-N-[2-(1H-pyrazol-1-yl)ethyl]- 3-Isoxazolecarboxamide, 5-(4-fluorophenyl)-N-[3-(1H-imidazol-1-yl)propyl]- Wnt pathway activator 2