4-[(4S,5R)-2-(4-methoxy-2-propan-2-yloxyphenyl)-4,5-bis[4-(trifluoromethyl)phenyl]-4,5-dihydroimidazole-1-carbonyl]piperazin-2-one CAS#: 1392830-09-9

4-[(4S,5R)-2-(4-methoxy-2-propan-2-yloxyphenyl)-4,5-bis[4-(trifluoromethyl)phenyl]-4,5-dihydroimidazole-1-carbonyl]piperazin-2-one

中文名称	4-[(4S,5R)-2-(4-methoxy-2-propan-2-yloxyphenyl)-4,5-bis[4-(trifluoromethyl)phenyl]-4,5-dihydroimidazole-1-carbonyl]piperazin-2-one
中文同义词
英文名称	CAYLIN-2
英文同义词	4-[(4S,5R)-2-(4-methoxy-2-propan-2-yloxyphenyl)-4,5-bis[4-(trifluoromethyl)phenyl]-4,5-dihydroimidazole-1-carbonyl]piperazin-2-one;Caylin-2 Exclusive;Caylin 2,Caylin2;2-Piperazinone, 4-[[(4R,5S)-4,5-dihydro-2-[4-methoxy-2-(1-methylethoxy)phenyl]-4,5-bis[4-(trifluoromethyl)phenyl]-1H-imidazol-1-yl]carbonyl]-, rel-;4-[4,5-bis(4-trifluoromethyl-phenyl)-2-(2-isopropoxy-4-methoxy-phenyl)-4,5-dihydro-imidazole-1-carboxyl]-piperazin-2-one;4-[4,5-BIS(4-TRIFLUOROMETHYL-PHENYL)-2-(2-ISOPROXY-4-METHOXY-PHENYL)-4,5-DIHYDRO-IMIDAZOLE-1-CARBOXYL]-PIPERAZIN-2-ONE;4-[4,5-BIS(4-TRIFLUOROMETHYL-PHENYL)-2-(2-ISOPROXY-4-METHOXY-PHENYL)-4,5-DIHYDRO-IMIDAZOLE-1-CARBOXYL]-PIPERAZIN-2-ONE;CAYLIN-1
CAS号	1392830-09-9
分子式	C32H30F6N4O4
分子量	648.5954192
EINECS号
相关类别
Mol文件	1392830-09-9.mol
结构式

密度	1.38±0.1 g/cm3(Predicted)
储存条件	Store at -20°C
溶解度	DMF：30mg/mL； DMSO：30mg/mL；乙醇：50mg/mL；乙醇:PBS (pH 7.2)(1:3)：0.025 mg/mL
形态	结晶固体
酸度系数(pKa)	14.26±0.20(Predicted)
颜色	White to off-white

Caylin-2 是一种 Nutlin-3 类似物，是一种 MDM2 抑制剂。Caylin-2 可与Bcl-XL 结合。