(Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxy-5-phenylpent-1-enyl]cyclopentyl]-N-(1,3-dihydroxypropan-2-yl)hept-5-enamide
| 中文名称 | (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxy-5-phenylpent-1-enyl]cyclopentyl]-N-(1,3-dihydroxypropan-2-yl)hept-5-enamide |
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| 中文同义词 | 化合物 BIMA SA |
| 英文名称 | (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxy-5-phenylpent-1-enyl]cyclopentyl]-N-(1,3-dihydroxypropan-2-yl)hept-5-enamide |
| 英文同义词 | (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxy-5-phenylpent-1-enyl]cyclopentyl]-N-(1,3-dihydroxypropan-2-yl)hept-5-enamide;Bimatoprost serinol amide;17-phenyl trinor Prostaglandin F2α serinol amide;5-Heptenamide, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-penten-1-yl]cyclopentyl]-N-[2-hydroxy-1-(hydroxymethyl)ethyl]-, (5Z)-;N-[(2-hydroxy-1-hydroxymethyl)ethyl]-9α,11α,15S-trihydroxy-17-phenyl-18,19,20-trinor-prosta-5Z,13E-dien-1-amide;Bima SA |
| CAS号 | 1175838-84-2 |
| 分子式 | C26H39NO6 |
| 分子量 | 461.59 |
| EINECS号 | |
| 相关类别 | |
| Mol文件 | 1175838-84-2.mol |
| 结构式 | ![(Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxy-5-phenylpent-1-enyl]cyclopentyl]-N-(1,3-dihydroxypropan-2-yl)hept-5-enamide 结构式](CAS/20180529/GIF/1175838-84-2.gif) |
(Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxy-5-phenylpent-1-enyl]cyclopentyl]-N-(1,3-dihydroxypropan-2-yl)hept-5-enamide 性质
| 沸点 | 737.3±60.0 °C(Predicted) |
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| 密度 | 1.231±0.06 g/cm3(Predicted) |
| 溶解度 | DMF：10mg/mL； DMSO：10mg/mL；乙醇：10mg/mL； PBS (pH7.2): .5 mg/mL |
| 酸度系数(pKa) | 13.97±0.10(Predicted) |
(Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxy-5-phenylpent-1-enyl]cyclopentyl]-N-(1,3-dihydroxypropan-2-yl)hept-5-enamide 用途与合成方法
Bima SA (Bimatoprost serinol amide) 是一种前列腺素类似物，具有用于青光眼研究的潜力。