ethyl 4-((3-(dimethylamino)propyl)imino)-6,8-dimethyl-1,4-dihydroquinoline-3-carboxylate manufacturers
- BMH-9
-
- $1980.00
-
2026-05-11
- CAS:457937-39-2
- Purity:
- Supply Ability: 10g
|
| | ethyl 4-((3-(dimethylamino)propyl)imino)-6,8-dimethyl-1,4-dihydroquinoline-3-carboxylate Basic information |
| | ethyl 4-((3-(dimethylamino)propyl)imino)-6,8-dimethyl-1,4-dihydroquinoline-3-carboxylate Chemical Properties |
| Boiling point | 461.3±45.0 °C(Predicted) | | density | 1.111±0.06 g/cm3(Predicted) | | pka | 9.45±0.28(Predicted) |
| | ethyl 4-((3-(dimethylamino)propyl)imino)-6,8-dimethyl-1,4-dihydroquinoline-3-carboxylate Usage And Synthesis |
| Description | BMH-9 is an inhibitor of RNA polymerase I. It acts by causing nucleolar stress and showing potent anticancer activity across many tumor types. | | Uses | BMH-9 (Compound Z54) is a modulator for nuclear receptor subfamily 2, group F, member 6 (NR2F6) (also known as nuclear orphan receptor Ear2)[1]. BMH-9 is an activator for p53 signaling pathway through interaction with DNA. BMH-9 inhibits proliferation of human cancer cells, exhibits antitumor efficacy in NOD-SCID mouse models[1]. | | References | [1] Lander HM, et al., Small Molecule Agonists and Antagonists of NR2F6 Activity in Humans. US20180214413. |
| | ethyl 4-((3-(dimethylamino)propyl)imino)-6,8-dimethyl-1,4-dihydroquinoline-3-carboxylate Preparation Products And Raw materials |
|