| Company Name: |
BOC Sciences
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| Tel: |
1-631-485-4226; 16314854226 |
| Email: |
info@bocsci.com |
| Products Intro: |
Product Name:M1001
CAS:874590-32-6
Remarks:Reach out to us for more information about custom solutions.
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1,1-dioxo-N-(2-pyrrolidin-1-ylphenyl)-1,2-benzothiazol-3-amine manufacturers
- M1001
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- $55.00
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2026-05-11
- CAS:874590-32-6
- Purity: 98.83%
- Supply Ability: 10g
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| | 1,1-dioxo-N-(2-pyrrolidin-1-ylphenyl)-1,2-benzothiazol-3-amine Basic information |
| Product Name: | 1,1-dioxo-N-(2-pyrrolidin-1-ylphenyl)-1,2-benzothiazol-3-amine | | Synonyms: | 1,1-dioxo-N-(2-pyrrolidin-1-ylphenyl)-1,2-benzothiazol-3-amine;3-((2-(Pyrrolidin-1-yl)phenyl)amino)benzo[d]isothiazole 1,1-dioxide;786-O,HIF/HIF Prolyl-Hydroxylase,inhibit,HIF-PH,M-1001,Hypoxia-inducible factors,HIFs,chronic kidney disease,M1001,Inhibitor,HEK293T,M 1001;1,2-Benzisothiazol-3-amine, N-[2-(1-pyrrolidinyl)phenyl]-, 1,1-dioxide;M1001, 10 mM in DMSO;M1001 | | CAS: | 874590-32-6 | | MF: | C17H17N3O2S | | MW: | 327.4 | | EINECS: | | | Product Categories: | | | Mol File: | 874590-32-6.mol |  |
| | 1,1-dioxo-N-(2-pyrrolidin-1-ylphenyl)-1,2-benzothiazol-3-amine Chemical Properties |
| Boiling point | 526.1±52.0 °C(Predicted) | | density | 1.40±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMSO : 250 mg/mL (763.59 mM; Need ultrasonic) | | form | A solid | | pka | 5.38±0.40(Predicted) | | color | Light green to green |
| | 1,1-dioxo-N-(2-pyrrolidin-1-ylphenyl)-1,2-benzothiazol-3-amine Usage And Synthesis |
| Uses | M1001 is a weak hypoxia-inducible factor-2α (HIF-2α) agonist. M1001 can bind to the HIF-2α PAS-B domain, with a Kd of 667 nM. M1001 can be used in chronic kidney disease research[1]. | | References | [1] Wu D, et al. Bidirectional modulation of HIF-2 activity through chemical ligands. Nat Chem Biol. 2019 Feb 25. DOI:10.1038/s41589-019-0234-5 |
| | 1,1-dioxo-N-(2-pyrrolidin-1-ylphenyl)-1,2-benzothiazol-3-amine Preparation Products And Raw materials |
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