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2'-Azido-2'-deoxyuridine

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2'-Azido-2'-deoxyuridine Basic information
Product Name:2'-Azido-2'-deoxyuridine
Synonyms:Uridine,2'-azido-2'-deoxy-;2'-AZIDO-2'-DEOXYURIDINE HPLC 98+%;2'-Azido-2'-deoxy-D-uridine;2''-AZIDO-D-URIDINE;2'-Az-dU;N3-dU;2'-N3-2'-dU;N3dUrd
CAS:26929-65-7
MF:C9H11N5O5
MW:269.22
EINECS:248-113-6
Product Categories:Nucleoside AnalogsChemical Ligation;Biochemicals and Reagents;Click Chemistry;Nucleosides, Nucleotides, Oligonucleotides;Organic Azides
Mol File:26929-65-7.mol
2'-Azido-2'-deoxyuridine Structure
2'-Azido-2'-deoxyuridine Chemical Properties
Melting point 149-153 °C
storage temp. 2-8°C
form powder to crystal
color White to Almost white
λmax260nm(lit.)
CAS DataBase Reference26929-65-7
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36-24/25-22
WGK Germany 3
F 8-10-21
HS Code 29349990
MSDS Information
ProviderLanguage
SigmaAldrich English
2'-Azido-2'-deoxyuridine Usage And Synthesis
Chemical PropertiesWhite powder
Uses2'-Azido-2'-deoxyuridine (N3dUrd) is a ribonucleotide reductase inhibitor. 2'-Azido-2'-deoxyuridine has anti-cancer activity[1]. 2'-Azido-2'-deoxyuridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
References[1] Kang SH, et al. Biological activity and phosphorylation of 2'-azido-2'-deoxyuridine and 2'-azido-2'-deoxycytidine. Nucleosides Nucleotides. 1998 Jun;17(6):1077-88. DOI:10.1080/07328319808004221
2'-Azido-2'-deoxyuridine Preparation Products And Raw materials
Tag:2'-Azido-2'-deoxyuridine(26929-65-7) Related Product Information
1-beta-D-Arabinofuranosyluracil Trifluridine Doxifluridine Floxuridine Zidovudine 2'-Deoxyuridine Uridine Sodium azide 2'-Amino-D-uridine (R)-3-AMINOTETRAHYDROFURAN uridine diphosphate glucose {= UDP-glucose} 3-FURANAMINE, TETRAHYDRO- 4-AZIDOBUTAN-1-OL 2'-Azido-2'-deoxyuridine 2-Azidoethanol 2'-AZIDO-2'-DEOXYURIDINE-5'-TRIPHOSPHATE LITHIUM SALT 5-Azido-2'-deoxyuridine 5'-triphosphoric acid 2'-azido-2'-deoxyuridine 5'-diphosphate